About the Book

A presentation of the opposing evolutionary forces that ultimately determine the health of host organisms and survival of pathogenic microorganisms. • Provides an in-depth examination of the complex ecosystems of the mammalian mucosa and the successful adaptations of microorganisms that enable them to effectively colonize these surfaces. • Covers colonization of the respiratory tract, the gastrointestinal tract, and the genitourinary tract and considers the various organisms present at these surfaces. • Contemplates aspects of bacterial colonization revealed by the most recent research including penetration of the mucous layer, innate immune effectors and their subversion, signaling of host cells by adherence factors, modulation of adherence, phase variation of colonization factors, and regulation of colonization effectors.

This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Table of Contents:
Table of Contents General Considerations 1. Structure and Function of Mucosal Surfaces, Jeff P. Pearson and Iain A. Brownlee 2. Defensins and Other Antimicrobial Peptides: Innate Defense of Mucosal Surfaces, Alexander M. Cole and Tomas Ganz 3. Mechanisms of Adaptive Immunity That Prevent Colonization at Mucosal Surfaces, Marcela F. Pasetti, Rosangela Salerno-Goncalves, and Marcelo B. Sztein 4. In Situ Monitoring of Bacterial Presence and Activity, Claus Sternberg, Michael Givskov, Leo Eberl, Karen A. Krogfelt, and Soren Molin Colonization of the Respiratory Tract 5. Role of Phosphorylcholine in Respiratory Tract Colonization, Jeffrey N. Weiser 6. Sialylation of the Gram-Negative Bacterial Cell Surface, Michael A. Apicella and Paul A. Jones 7. Competitive and Cooperative Interactions in the Respiratory Microflora, Adam J. Ratner 8. Bacterial Adherence and Tropism in the Human Respiratory Tract, Mumtaz Virji 9. Immunoglobulin A1 Proteases of Pathogenic and Commensal Bacteria of the Respiratory Tract, Mogens Kilian and Jesper Reinholdt 10. Genetic Exchange in the Respiratory Tract, Christopher G. Dowson 11. Regulation of Respiratory Pathogens in Response to Environmental Conditions, Peggy A. Cotter Colonization of the Gastrointestinal Tract 12. Microbiota of Mucosal Surfaces in the Gut of Monogastric Animals, Gerald W. Tannock 13. Interactions of Commensal Flora with the Human Gastrointestinal Tract, James P. Nataro 14. Quorum Sensing in the Gastrointestinal Tract, James B. Kaper, Christopher Pritchett, and Jane Michalski 15. Role of the Mucous Layer in Bacterial Colonization of the Intestine, David C. Laux, Paul S. Cohen, and Tyrrell Conway 16. Role of Flagella in Mucosal Colonization, Jorge A. Giron 17. Tissue Tropism in Intestinal Colonization, Elizabeth L. Hartland, Roy M. Robins-Browne, Alan D. Philips, and Gad Frankel 18. Aggregation and Dispersal on Mucosal Surfaces, James P. Nataro and Angela Jansen 19. Signal Transduction in the Intestinal Mucosa, Beth A. McCormick 20. Pathogen Gene Expression during Intestinal Infection, Susan M. Butler, Anna D. Tischler, and Andrew Camilli 21. Mechanisms of Salmonella enterica Serotype Typhimurium Intestinal Colonization, Caleb W. Dorsey, Manuela Raffatellu, Robert A. Kingsley, and Andreas J. Baumler 22. Colonization and Invasion of Humans by Entameoba histolytica, Kristine M. Peterson and William A. Petri, Jr. Colonization of the Genitourinary Tract 23. Role of Phase and Antigenic Variation in Neisseria gonorrhoeae Colonization, Amy N. Simms and Ann E. Jerse 24. Allelic Variation of the FimH Lectin of Escherichia coli Type 1 Fimbriae and Uropathogenesis, David L. Hasty, Xue-Ru Wu, Daniel E. Dykuizen, and Evgeni V. Sokurenko 25. Fimbriae, Signaling, and Host Response to Urinary Tract Infection, Niamh Roche, Goran Bergsten, Hans Fischer, Gabriela Godaly, Heikke Irjala, Ann charlotte Lundstedt, Patrik Samuelsson, Majlis Svensson, and Catharina Svanborg 26. Urease, Urolithiasis, and Colonization of the Urinary Tract, Harry L. T. Mobley 27. Polymicrobial Bacteriuria: Biofilm Formation on Foreign Bodies and Colonization of the Urinary Tract, David J. Stickler 28. Colonization of the Vagina and Urethral Mucosa, Gregor Reid