Charles MacKayCharles Mackay?did his Ph.D at Melbourne University, and worked at the Basel Institute for?Immunology, LeukoSite Inc. and Millennium Therapeutics in Boston, before moving the Moahs in 2009. Charles Mackay is accomplished in the fields of inflammation GPCR biology, cell migration and cytokine biology. Charles is the leading advocate of a new hypothesis to explain many ‘western life style’ diseases, that diet, gut microbes and their metabolites are responsible. Eminent immunologist Professor Charles Mackay is exploring an exciting new concept- that nutrition and the gut microbiome have profound influences on physiology, particularly immune responses. Charles Mackay demonstrated that dietary fiber and its breakdown fermented products, the short chain fatty acids (SCFAs) influence gut homeostasis, the composition of the gut microbiota, immune tolerance, and inflammatory responses. His research focuses on cellular and molecular pathways, such as the 'metabolite-sensing GPCRs, and epigenetic pathways including HDAC inhibition Read More Read Less
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