David Compton

David was born and raised in Missouri where he received his BA degree in Chemistry from Washington University in St. Louis. Subsequently he received his PhD from the Department of Pharmacology and Toxicology at the University of Texas Medical Branh in Galveston. His dissertation research, funded in part by an Individual Predoctoral Grant from the Scottish Rite Schizophrenia Foundation, was on the dopaminergic and cholinergic neurotransmission effects of antipsychotic medications. At graduation David received both the Academic Excellence Award and the Jason E. Perlman Research Award. He conducted postdoctoral research on the neuropharmacology of drugs of abuse at the MCV (Medical College of Virginia) campus of VCU (Virginia Commonwealth University) in Richmond. During his 2 years on a NIDA Institutional Training Grant, David was awarded a Pharmaceutical Manufacturers Association (now PhRMA) Foundation Award funding postdoctoral research into "Receptor and Nonspecific Mechanisms of Cannabinoid-Induced Alterations of Neurotransmission." Subsequently he received a NIDA Individual Postdoctoral Grant to conduct research on the structure-activity relationships of the neurochemical / neurobehavioral effects of cannabinoids). During his career as Assistant and Associate Professor at MCV-VCU in the Department of Pharmacology and Toxicology, David taught professional students (medical, pharmacy, etc), was the Advisor and/or Committee member of graduate (Masters and PhD) students, and continued research on drugs of abuse funded by NIDA grants (as Individual [Primary Investigator], as Co-Investigator, and as part of a multi-faculty Center Grant) on cannabinoids, stimulants, and anabolic steroids. David published extensively in peer reviewed journals, co-authored books on abuse liability, and co-authored chapters in medical pharmacology texts. One of his more prized accomplishments was the Students' Choice Award for Faculty of the Year in 1994. Though still currently an Affiliate Associate Professor at VCU, after leaving academia, David gained valuable GLP (Good Laboratory Practices) experience in preclinical / nonclinical toxicology as a Study Director on FDA-mandated regulatory studies in general toxicology, reproductive toxicology, and safety pharmacology while working for Huntingdon Life Sciences, a CRO (Contract Research Organization) at the Princeton Research Center in New Jersey. Subsequently, he was an Associate and then Principal Scientist at the Schering-Plough Research Institute focussing on drug development as the Drug Safety Evaluation representative to Project Teams, prior to his positions as Principal Scientist and currently Lead - Toxicologist and Project Team Expert within Preclinical Safety at Sanofi U.S. in New Jersey, where he has served since 2007 as a Subject Matter Expert with the DALA (Drug Abuse Liability Assessment) group advising Project Teams on development issues related to abuse potential of NMEs [New Molecular Entity(ies)].

David has 30 years of combined academic, contract laboratory, and pharmaceutical experience in the fields of neuroscience/neuropharmacology, abuse liability/assessment, education, study directing, toxicology, and preclinical drug development. In 1999 he was certified as a Diplomate of the American Board of Toxicology (DABT). He has been a full member of ACT (American College of Toxicology) since 1997 and has served on numerous elected positions. As of 2013, he is serving his second 3-year elected term on the Council (board) of ACT, and concluded as of 2015 his second year as Chair of the ACT Website Committee. Since 2012 he has also served on the Editorial Board of the International Journal of Toxicology. He has been a full member of SOT (Society of Toxicology) since 2011, and is currently a full member of both CPDD (College on Problems of Drug Dependence) and the Society for Neuroscience, having first joined each as an associate/student member in the 1980's. David has presented numerous scientific posters, given multiple symposia presentations, as well as organized and served as the chair of symposia on drug abuse/liability. In 2010 he was the Sanofi U.S. representative to PhRMA responsible for generating the industry response to the FDA draft guidance on Assessment of Abuse Potential of Drugs. David has been a member of the CCALC (Cross-Company Abuse Liability Consortium) since 2007, has been a Co-Lead of the PAL (Preclinical Abuse Liability) sub-group of CCALC since election in 2013, and has been part of the CCALC organizing committees for the 2008 and 2015 FDA-Industry Dialogue sessions on abuse potential issues, as well as the By-Laws committee of 2014-2015 to establish CCALC as a legal, scientific, non-profit organization. In 2002 David was a founding member of the now defunct, non-profit New Jersey Brain Bee Association, which sponsored an annual competition (until 2011) for high school students (qualifying the winner to compete in the International Brain Bee competition co-sponsored by the Society for Neuroscience).