Denis NobleDenis Noble, C.B.E., Ph.D., F.R.S. is a British biologist who held the Burdon Sanderson Chair of Cardiovascular Physiology at the University of Oxford from 1984 to 2004 and was appointed Professor Emeritus and co-Director of Computational Physiology.He is one of the pioneers of systems biology. Professor Noble developed the first viable mathematical model of the working heart in 1960 using his discovery, with his supervisor Otto Hutter, of two of the main cardiac potassium ion channels. These discoveries were published in Nature (1960) and The Journal of Physiology (1962). The work was later developed with Dick Tsien, Dario DiFrancesco, Don Hilgemann and others to become the canonical models on which more than 100 cardiac cell models are based today. He was elected President of the International Union of Physiological Sciences (IUPS) at its Congress in Kyoto in 2009 and was re-elected for a second term at the 2013 Congress in Birmingham, UK. He is the author of the first popular book on systems biology, The Music of Life, and his most recent lectures concern the implications for evolutionary biology. Professor Noble has published more than 500 papers and 11 books. https://en.wikipedia.org/wiki/Denis_Noble Read More Read Less