Paul Spearman

Paul SpearmanPaul Spearman, MD is the Albert B. Sabin Professor and Director of Infectious Diseases at Cincinnati Children's Hospital Medical Center. His laboratory studies fundamental aspects of HIV biology and develops new vaccines for human pathogens. HIV assebly processes are a major focus of the laboratory, including the trafficking of the HIV envelope glycoprotein and its interaction with essential host factors. A related project studies how HIV interacts with macrophages and microglia. Dr. Spearman and his colleagues in the CCHMC Vaccine and Treatment Evaluation Unit (VTEU) are engaged in the design and performance of clinical trials for new vaccines in adults and children, with a special interest in employing cutting-edge technologies to define innate and adaptive immune responses to vaccines. Dr. Spearman is currently leading trials for Ebola and RSV vaccine development.

Dr. Spearman serves on the Board of Scientific Counselors for NCI, the Vaccines and Related Biological Products Advisory Committee for the FDA, and is Past President of the Pediatric Infectious Diseases Society (PIDS). Beyond his research interests, Dr. Spearman is a Pediatric ID clinician and enjoys caring for children and mentoring future leaders in Infectious Diseases. Read More Read Less

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Molecular Medical Microbiology46 %
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HIV Interactions with Host Cell Proteins37 %
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HIV Interactions with Host Cell Proteins
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American Educational History Journal Vol 41 Issue 1 & 257 %
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American Educational History Journal Vol 41 Issue 1 & 250 %
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Reclaiming Our StoriesNR
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Reclaiming Our Stories 226 % NR
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