This book on "Acquired Mitochondropathy" offers a new perspective on the understanding and the treatment of chronic ailments. Addressing a new paradigm deemed necessary, since in one of every four adults in the western world chronic ailments are on the rise. Resulting from energy dysfunction of cellular organelles, the mitochondria, the most of the common symptoms the physician faces during medical consultation are presented. An increasing focus on chronic disabilities presents difficulties for the busy practitioner, since patients typically describe a complex pattern of discomfort, disability, and distress, with pain affecting physical, social, and psychological functioning, which have to be put in the proper perspective. Since clinicians must efficiently condense widely varied symptomatic descriptions into characteristic patterns to permit accurate diagnosis and implement effective treatment, this book serves as a useful educational resource for the healthcare provider.

Table of Contents:
Foreword 1.Introduction 2. The mitochondrion - essential part in cellular function 2.1. Function of mitochondria - the electron transport chain 2.2. Function of mitochondria- oxidative phosphorylation References 3. Definition of mitochondropathy - nitrosative stress 3.1. Significance of T1-Th2 Switch within the Immune System References 4. Nitric oxide, a Janus two-faced molecule 4.1. Biological functions of nitric oxide 4.2. Nitric oxide-peroxynitrite, causes for multisystem ailments References 5. Representative ailments with excess nitric oxide formation 5.1. Chronic fatigue syndrome, symptom of mitochondrial failure 5.2. Excess formation of nitric oxide in inflammation 5.3. Excessive nitric oxide formation damage mitochondria References 6. Principles in nitrosative stress 6.1. Tetrahydrobiopterin impaired by nitrosative stress References 7. Nitrosative stress in diverse multisystem diseases 7.1. Factors leading to a reduction of BH4 7.1.1. Local malfunction of mitochondria related to multisystem diseases 7.1.2. Factors Driving Nitrosative Stress 7.2. Exogenic toxicity leading to mitochondrial function 7.2.1. Stress hormones on mitochondrial function. 7.2.2. Additives in food chain with mitochondrial toxicity 7.2.3. Chemical substances - originators of mitochondropathy 7.2.3.1. Complex Regional Pain Syndrome, a mitochondrial disease? 7.3. Neurodegeneration resulting from blockade in the energy pathway 7.3.1. Neurodegenerative diseases have a common denominator 7.3.2. Mitochondropathy and Neurodegeneration in different disease states 7.3.3. Chronic Fatigue syndrome, Fibromyalgia caused by mitochondrial failure7.3.4. Chronic fatigue caused by mitochondrial failure 7.3.4.1. Additional symptoms in chronique fatigue and fibromyalgia 7.3.4.2. Explaining the Fatigue Problems to CFS Patients 7.3.5. Hormonal Problem in CFS - Hypothyroidism, Adrenal Insufficiency 7.4. Symptoms of mitochondropathy of the CNS 7.4.1. Fibromyalgia closely related to mitochondropathy 7.4.1.1. How to indentify problems of mitochondria 7.4.1.2 .Medium chain fatty acids for restoration of mental capacity 7.4.2. Situations developing into hypoglycemia 7.4.2.1. Sugar and fast carbohydrates are addictive 7.4.2.2. Problems in digestion: Bacteria and yeast in the upper gut 7.4.2.3. Tests for bacteria in the upper gut fermentation 7.5. The Methylation Cycle-hypothesis for pathogenesis of fatigue 7.5.1.Creating a healthy digestive tract 7.5.1.1. Diagnosis/Treatment of poor pancreatic function 7.5.1.2. Free radicals from the liver resulting in mitochondropathy References 8. Points to consider in therapy of mitochondropathy 8.1.Phospholipids restoring cellular function 8.1.1. Resetting the recommended daily allowance (RDA) 8.2. Toxic stress in Western world (Xenobiotics) 8.2.1. Glycation end-products impede supply of cholesteroland fats to neurons. 8.3. Mitochondria involved in mutation to cancer cells? 8.4. Avoiding inflammation, mediator of nitrosative stress 8.5. Therapeutics for normal mitochondrial function 8.6. Basics in therapy of mitochondrial-related diseases 8.7. Reasoning supplemental therapy in mitochondropathy 8.8. Food used as medicine in mitochondropathy 8.9. Newer therapeutic options in mitochondropathy 8.10. Mechanisms of Action of Agents for therapy in CFS-FMS-Parkinson-Alzheimer8.11. New avenues in treatment of mitochondropathy References 9.0 Lab tests for mitochondropathy, nitrosative stress Appendix: List of certified Labs in Europe for diagnosing mitochondropathy