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Artificial Metalloproteins: Volume 720(Volume 720 Methods in Enzymology)

Artificial Metalloproteins: Volume 720(Volume 720 Methods in Enzymology)

          
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About the Book

Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-like Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more. Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.

Table of Contents:
1. Incorporating Non-Native Cofactors into Heme Proteins Christopher Lemon 2. Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-like Cofactors Samuel Mann 3. Cobalt-Substituted Hemoprotein Expression Andrew Buller 4. Rationally designed directed evolution of cytochrome P450 enzymes Shyamalava Mazumdar 5. De novo design of a switchable ??-helical hemoprotein Vincent Louis Pecoraro Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme 6. Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes Woon Ju Song 7. Development of a PQQ-Dependent Artificial Metalloprotein Lisa Olshansky 8. Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme Akira Onoda 9. Design and Application of Nonheme Iron Enzymes Xiongyi Huang Part C: Secondary Sphere Modulation for Metallocofactor Activation 10. Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds Yi Lu 11. De Novo-Designed Artificial Cu Proteins and Electron Transfer Saumen Chakraborty 12. Design and Evaluation of Biocatalysts for Energy-Related Reactions Kara Bren Part D. Superstructural Control: Tertiary and Quaternary Effects in Metalloprotein Design 13. Breaking Symmetry: Metal-Guided Assembly of Heterotrimeric Coiled Coils Vincent Louis Pecoraro and Salvatore La Gatta 14. Engineering Conformationally Switchable Artificial Metalloproteins Lisa Olshansky 15. Chemical Methods to Stabilize Segments of Metalloproteins in the Form of Peptides Andy Nguyen 16. Design and Production of De Novo Protein Nanowires Ross Anderson


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Product Details
  • ISBN-13: 9780443415739
  • Publisher: Elsevier Science Publishing Co Inc
  • Publisher Imprint: Academic Press Inc
  • Height: 229 mm
  • No of Pages: 412
  • Sub Title: Volume 720
  • Width: 152 mm
  • ISBN-10: 0443415730
  • Publisher Date: 01 Oct 2025
  • Binding: Hardback
  • Language: English
  • Series Title: Volume 720 Methods in Enzymology
  • Weight: 448 gr


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