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Biomolecular Data: A Resource in Transition

Biomolecular Data: A Resource in Transition

          
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About the Book

Nucleic acid and protein sequence data are accumulating at an ever-increasing rate as a result of the efforts of scientists from a wide range of biological disciplines in many countries. These researchers need to be able to compare their results quickly and accurately with good quality information held in databanks throughout the world. This book discusses the organization and maintenance of databanks holding this information and poses a range of possible solutions to this formidable challenge faced by computer scientists. The study should be of benefit to biochemists, geneticists, molecular biologists, protein chemists and researchers in related fields.

Table of Contents:
Part 1 The emergence of biomolecular data management: data proliferation - a challenge for science and for CODATA, A.E.Busard; how much sequence data the databanks will be processing in the near future, C.Burks; CODATA helps the development of sequence databases, B.Keil; the structure of nucleotide sequence databases, G.N.Cameron; hte National Library of Medicine, D.A.B.Lindberg; a method for the rapid and accurate deposition of nucleic acid data in an acceptably annotated form, R.T.Walker. Part 2 Managing biomolecular data: compilation of tRNA sequences and sequences of tRNA genes, M.Sprinzl; problems in maintaining a protein sequence database, Y.Seto et al; collection and standardization of crystal structure data by the protein data bank, T.F.Koetzle et al; quality control for a rapidly changing database, W.C.Barker et al; the database crisis - problems and solutions, efforts of an emerging Japanese database, A.Tsugita; the human gene mapping library, R.L.Miller; factual databases in basic research, R.J.Roberts; the Berlin RNA database - problems and solutions, J.Wolters and V.Erdmann. Part 3 Using biochemical data: the problem with GENBANK, E.A.Kabat; some perspective of a database user, R.M.Stephens; why industrial scientists are interested in the future development of sequence databases, J.L.Modelevsky; availability of nucleic acid sequences data in Poland, J.Augustyniack; international protein and peptide database, B.Wittman-Liebold; IRIS - integrated RNA information for systematics, H.Hori and Y.Saton; expert system simulations as active learning environments, D.L.Brutlag; integrated access to sequence and structural data - principles of design of comprehensive databases for molecular biology, A.Lesk; searching for codes in the sequences, E.N.Trifonov; semantic and syntactic patterns in the genetic language, T.F.Smith; databases - what's there and what's needed, M.Kanehisa. Part 4 Future trends in the management of biomolecular data: toward global data interfacing, D.R.Masys; linking sequence databases to the current scientific literature, D.A.Benson; global interfacing of people, places, data and knowledge - calm seas and prosperous voyage?, M.I.Krichevsky; global data exchange on compact disk read-only memory, F.R.Blattner; BIONET - an NIH computer resource for molecular biology, D.L.Brutlag and D.Kristofferson; the database as a communication medium, J.W.Fickett; some ideas towards an electronic information centre for biotechnology, A.Fletcher; computer education in biochemistry, chemistry and molecular biology, V.Erdmann et al; sources of data in the GENBANK database, C.Burks; to publish or not to publish DNA sequences, R.D.Wells; to publish or not to publish, P.Kahn and L.Philipson.


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Product Details
  • ISBN-13: 9780198542476
  • Publisher: Oxford University Press
  • Publisher Imprint: Oxford University Press
  • Height: 235 mm
  • No of Pages: 382
  • Spine Width: 21 mm
  • Weight: 633 gr
  • ISBN-10: 019854247X
  • Publisher Date: /03/1989
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Sub Title: A Resource in Transition
  • Width: 155 mm


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