This book provides a comprehensive understanding of cell signaling, molecular interactions, and their implications for human health and diseases. It introduces fundamental principles underlying cell communication through signaling molecules and their diverse transmission and reception mechanisms, highlighting their role in intercellular communication through voltage- and ion-gated channels, immunological and neuron synapses, and rhinovirus–receptor interaction involved in pathogenesis and disease development. Toward the end, the book highlights the profound implications of altered cell signaling pathways in the inflammation and immune response followed by the progression of various disorders, including cancer, endocrine disorders, and neurological illnesses. It explores the diagnostic and therapeutic implications of cell signaling in targeted therapies, highlighting advanced techniques for detecting signaling molecules and innovative therapeutic approaches to inspire new developments in precision medicine. It serves as an important resource for academics, students, and professionals in the fields of cell biology and biomedical sciences.
Key Features:
- Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and disease
- Introduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathways
- Focuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behavior
- Examines the molecular aspects of cell surface adhesion receptors, elucidating protein–protein interactions, signaling cascades, and enzyme–substrate interactions
- Discusses the impact of cell signaling on inflammation, cancer, and endocrine and neurological disorders
Table of Contents:
1. Introduction to cell signaling
Ishtiaq Ali, Muhammad Junaid, Ahmad Tariq, Fazli Wahid, Muhammad Imran Khan
2. Regulation of Cell Signaling Cascades
Habab Ali Ahmad, Muhammad Ibrahim, Fazli Wahid, Muhammad Imran Khan
3. Cellular Receptors and Cell Signaling
Maleeha Azhar, Aroob Hasan Khan, Aroosa Younis Nadeem, Areej Fatima, Adeeb Shehzad
4. Signal Transduction and Integral Membrane Proteins
Zain Saeed, Zohra Jabeen, Sehrish Kakakhel, Saira Justin, Aneela Javed
5. Antigen-Antibody Interaction in cell signaling
Saman Noor, Anam Fatima, Iman Fatima, Gul Naz, Aneela Javed
6. Immunological and Neuron Synapses
Muhammad Salman Khalid, Somia Mazhar, Adeeb Shehzad
7. Rhinoviruses receptors and their interactions
Areej A. Sattar, Ariba Qaiser, Sobia Manzoor
8. Role of ligand and voltage gated ion channels in cell signaling
Maham Maharangaiz, Hira, sadaf Mumtaz, Rumeza hanif, Aneela Javed
9. Hormones and Receptors Interaction in Cell Signaling
Tehmina Bibi, Shahar Bano, Eun Kyoung Seo, Salman Khan
10. Signaling Networks in Development and Differentiation
Aroosa Younis Nadeem, Areej Fatima, Maleeha Azhar, Adeeb Shehzad
11. Cell Signaling and Metabolism
Saadia Zahid*, Sanila Amber, Laila tul Qadar, Akasha Khurshid
12. Inflammatory Signaling and Immune Response
Naseem Zehra, Zia Uddin, Muhammad Imran Amir Zada, Muhammad Ikram
13. Cell Signaling in Cancer
Khoula Sharif Mughal, Nabi Shah, Muhammad Naeem, Muhammad Ikram
14. Cell signaling pathways in endocrine diseases
Gauhar Rehman, Adil Sher
15. Cell Signaling in Neurological Disorders
Muhammad Ibrar Khan, Muhammad Junaid, Salman Khan
16. Cell Signaling and Diagnosis
Areej Fatima, Ammad Jamil, Maleeha Azhar, Aroosa Younis Nadeem, Adeeb Shehzad
17. Signal Transduction and Targeted Therapies
Ayesha Khan, Ayesha Riaz, Asima Saeed, Muhammad Imran Khan
18. Role of cell signaling in drug development
Taimoor Musharaf, Anoosha Ahmed, Muhammad Asim Siddique, Wajahat Sultan Abbasi, Saadia Andleeb
