When discussing dementia, the medical literature tends to focus on Alzheimer's disease, leaving other dementias, such as those relating to cerebrovascular disease, somewhat neglected, despite being a common cause of cognitive decline in later life. However, in recent years there has been a remarkable transformation in our knowledge about the role of vascular factors in cognitive decline and dementia. It is now recognized that cerebrovascular disease influences clinical expression of cognitive and non cognitive features in a variety of cognitive disorders, including Alzheimer's disease itself. Cerebrovascular Disease, Cognitive Impairment and Dementia reviews what is now known about the relationship between cerebrovascular disease and dementia. It describes new knowledge of how vascular processes interact with neuro-degenerative ones, and how both appear to be risk factors for the other. The book contains contributions from leading international experts and covers epidemiology, diagnosis, clinical features, investigations (including neuroimaging), management, and service and caregiver issues. The second edition of this pioneering text is completely revised and emphasizes the primary and secondary prevention of cerebrovascular disease and the treatment of cognitive impairment. A truly comprehensive yet accessible text which puts basic research findings in a clinically relevant context, this book will appeal to psychiatrists, neurologists, geriatricians, allied health professionals, and others involved in the care of patients with cognitive impairment and dementia.

Table of Contents:
CLASSIFICATION AND DIAGNOSIS Historical Overview, L. Gustafson Classification and Diagnostic Criteria, R. Stewart EPIDEMIOLOGY AND RISK FACTORS Epidemiology of Vascular Dementia in Europe, I. Skoog and O. Aevarsson Epidemiology of Vascular Dementia in North America, R. Eastwood and J. O'Brien Epidemiology of Vascular Dementia in Japan, A. Homma and K. Hasegawa Epidemiology of Vascular Dementia in China, X. Yu and Y. Shen Epidemiology of Vascular Dementia: Meta-analysis, A.F. Jorm and R. Kumar The Epidemiology of Vascular Dementia: An Overview and Commentary, A.F. Jorn and J. O'Brien PATHOPHYSIOLOGY OF CEREBROVASCULAR DISEASE - WITH REFERENCE TO DEMENTIAS The Neuropathology of Vascular Dementia and Its Overlap with Alzheimer's Disease, A. Brun White Matter Pathology in Vascular Dementia, E. Englund Neurotransmitter Changes in Vascular Dementia, J.A. Court, E.K. Perry, and R.N. Kalaria Hereditary Forms of Vascular Dementia, M. Dichgans Homocysteine, Cerebrovascular Disease, Coginitive Function, and Aging, K.L. Tucker, T.M. Scott, and M. Folstein CLINICAL FEATURES Clinical Pathological Correlates, L. Gustafson and U. Passant Behavioral Neurology of Sporadic Vascular Dementia, K.M. Moksnes and A. Wallin Vascular Mild Cognitive Impairment and Cognitive Impairments After Stroke, S. Stephens, S. Sadler, E. Rowan, M. Bradbury, and C. Ballard Neuropsychological Profile of Vascular Cognitive Cognition and Neuropsychology, T.M. Scott and M. Folstein Noncognitive Symptoms, R. Barber ASSESSMENT AND INVESTIGATIONS Clinical Assessment and Investigation, A. Thomas Neuroimaging in Vascular Dementia, J. O'Brien MANAGEMENT Primary Prevention, S.M. Davis Secondary Prevention: Medical Management of Established Cerebrovascular Disease, L. Flicker and N.T. Lautenschlager Treatment of Cognitive Impairment in Vascular Dementia, D. Wilkinson Management of Psychiatric Disorders Associated with Cerebrovascular Disease, J. Stratford and D. Ames Vascular Dementia: Consequences for Family Carers and Implications for Management, H. Brodaty, A. Green, and L.-F. Low The Challenges in Provision of Longterm Care and in Understanding Behavioral Disorders in Cerebrovascular Disease and Dementia , E. Chiu Index