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Designing an antimicrobial and cell-adhesive multilayer

Designing an antimicrobial and cell-adhesive multilayer

          
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About the Book

In this work surface modifications were developed that bear cell-adhesive as well as antimicrobial properties. Fast cell adhesion and wound healing is desired for biomaterials since otherwise the material would be recognized as a foreign body and infectious bacteria could enter the cavity between material and tissue. Plasma polymerization was used as the deposition technique since a broad range of materials can be coated independent of their composition. As a cell-adhesive coating plasma polymerized allylamine was chosen since it is cell-friendly and offers a platform for wet chemical modifications such as grafting of fibronectin. Furthermore, it serves as a barrier layer for zinc and silver containing sub-layers that exhibit antimicrobial properties due to the release of zinc and silver. The layer systems were spectroscopically and microscopically investigated. Cell-adhesive and antimicrobial properties were tested with various types of cells and bacteria.


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Product Details
  • ISBN-13: 9783838133430
  • Publisher: Sudwestdeutscher Verlag Fur Hochschulschriften AG
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Spine Width: 8 mm
  • Width: 152 mm
  • ISBN-10: 3838133439
  • Publisher Date: 25 May 2012
  • Height: 229 mm
  • No of Pages: 132
  • Series Title: English
  • Weight: 204 gr


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Designing an antimicrobial and cell-adhesive multilayer
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