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Developments in Dementia and Functional Disorders in the Elderly

Developments in Dementia and Functional Disorders in the Elderly

          
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About the Book

The contributors to this volume present the advances and current controversies in the study and treatment of dementia, memory impairment, depression and other functional disorders in the elderly. The book is divided into three sections: part one covers Alzheimer's disease, vascular and Lewy body dementia and ageing-associated cognitive decline falling short of dementia; part two presents the results of clinical trials of various recently developed antidementia drugs, drug trial methodology, and the possible clinical and financial implications arising from the introduction of these drugs. The final section discusses the management of depression and other functional disorders in the elderly, both with regard to the environment in which it takes place and the form of treatment employed, and, in this context, the novel antidepressants and new major tranquilizers are reviewed. Special features: outline latest information on the molecular mechanisms behind Alzheimer's disease; discuss the different views of the significance of Lewy body dementia; report on the most recent trials of antidementia drugs; and give the new international definition of the controversial ageing-associated cognitive decline.

Table of Contents:
Part 1 Update on the dementias and disorders of memory: plaques, tangles and genes - the molecular biology of Alzheimer's disease, Simon Lovestone; cortical Lewy body disease - the view from Newcastle, Ian G. McKeith; cortical Lewy body disease - an alternative view, E. Jane Byrne; vascular dementia in perspective, Martin B. Brown; report - ageing-associated cognitive decline, Raymond Levy. Part 2 Drug trials in dementia - new compounds, methodology and implications: two parallel-group studies of tacrine in Alzheimer's disease, Steven I. Gracon and William G. Berghoff; nimodipine in the treatment of senile dementias, Lucio A.A. van Rooijen et al; pharmacodynamics and early clinical studies with S12024 in Alzheimer's disease, G. Guez et al; neurotransmitter-based treatment of Alzheimer's disease - the example of velnacrine, Klaudius Siegfried; activities of daily-living scales - their development and future, Saskia Teunisse; measuring change in dementia - the reliability of clinical global assessments, Harry Boothby; economic evaluation and dementia, Martin Knapp et al; tacrine and its successors - breakthrough or blind alley?, Brice Pitt. Part 3 Functional illness in the elderly: antidepressants in the elderly, Robert C. Baldwin et al; novel antipsychotics in the elderly, Andre L. Phanjoo; managing depression within a day hospital, David Jolley; management of depression by a community mental health team, Michael Philpot, et al.


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Product Details
  • ISBN-13: 9781871816273
  • Publisher: Wrightson Biomedical Publishing Ltd
  • Publisher Imprint: Wrightson Biomedical Publishing Ltd
  • Language: English
  • ISBN-10: 1871816270
  • Publisher Date: 01 Apr 1995
  • Binding: Hardback
  • Weight: 498 gr


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