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Field Flow Fractionation: Principles and Applications

Field Flow Fractionation: Principles and Applications

          
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About the Book

Comprehensive, up-to-date, and user-centered one-stop reference on principles and applications of Field flow fractionation (FFF), a highly versatile separation technology Field Flow Fractionation Principles and Applications offers a comprehensive and topical one-stop reference on field flow fractionation (FFF), an important separation technique which has been proven successful in the analysis of natural and engineered nanoparticles, pharmaceuticals, proteins, polymers, soils, and food. After introductory chapters on theory, principles, and instrumentation, a tutorial-style user guide addresses typical users' questions and problems. In the application part, the separation of all relevant particle classes is discussed by international experts. Sample topics covered in Field Flow Fractionation Principles and Applications include: Historical perspectives of the technique, normal versus steric versus hyperlayer modes, retention resolution, and fractionation power FFF techniques, including flow (asymmetric, frit inlet, and outlet), sedimentation, thermal, electric, and other novel techniques such as 2D How to determine if FFF is the correct choice and if it is being implemented correctly, along with general optimization strategies including carrier fluid, calibration, and reproducibility Sample overloading and recovery, detector selection, troubleshooting, and performance of other fractionation techniques Both beginners and experienced chemists and researchers can confidently rely on Field Flow Fractionation Principles and Applications to confirm their own understanding and to improve their FFF methods and interpretation of their results.

Table of Contents:
PART I: THEORY Chapter 1. The Basics FFF Overview Historical perspectives Normal vs steric vs hyperlayer modes Retention Resolution, fractionation power Chapter 2. FFF techniques AF4 - Flow FFF (asymmetric, frit inlet and outlet) HF5- Hollow-fiber flow FFF Sedimentation FFF Thermal FFF Electrical FFF Novel techniques (including 2D-FFF) Chapter 3. User guide Which FFF is right for you? How to use FF correctly? General optimization strategies: carrier fluid, calibration, reproducibility Sample overloading Sample recovery Which detector to choose? How to troubleshoot FFF? (in general terms) Chapter 4. Other physical fractionation techniques: focus on performance as compared to the FFF Filtration/Ultrafiltration Centrifugation/ultracentrifugation Size exclusion chromatography Liquid chromatography Microfluidics Precipitation PART II: APPLICATIONS Chapter 5. Polymer and latex Chapter 6. Biological particles: Virus, DNA/RNA, drug delivery Chapter 7. Nanoparticles in water and soil Chapter 8. Manufactured nanoparticles Chapter 9. Protein, enzymes Chapter 10. Cell separations - blood and algal cells Chapter 11. Food industry - Starch Chapter 12. Pharmaceutical industry - drug delivery Chapter 13. Disease diagnosis


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Product Details
  • ISBN-13: 9783527340682
  • Publisher: Wiley-VCH Verlag GmbH
  • Publisher Imprint: Blackwell Verlag GmbH
  • Height: 244 mm
  • No of Pages: 288
  • Spine Width: mm
  • Width: 170 mm
  • ISBN-10: 3527340688
  • Publisher Date: 08 Oct 2025
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Sub Title: Principles and Applications


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