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Heart Failure in the Child and Young Adult: From Bench to Bedside

Heart Failure in the Child and Young Adult: From Bench to Bedside

          
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About the Book

Heart Failure in the Child and Young Adult: From Bench to Bedside, Second Edition highlights unique aspects of heart failure in the young. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure and then progresses through diagnosis, management, treatment, and surgery, finally concluding with advanced special topics, including genetics, self-management, and nanomedicine. This new edition covers advancements in the field, including additional chapters and discussion on biomarkers, neuromuscular disease, quality of life, palliative care, and the impact of COVID-19 in myocarditis and multisystem inflammatory syndrome in children. It will serve as an indispensable reference to basic science researchers in cardiology, pediatrics, cardiologists, and pediatric cardiologists.

Table of Contents:
Section I Basic science of heart failure 1. From molecular and cellular mechanisms to models of heart failure 2. Cardiovascular receptors and signaling in heart failure 3. Heart failure in the child and young adult: From bench to bedside: Inflammatory mediators in heart failure 4. Transcriptional regulation, epigenetic regulation, and transcriptomics of pediatric heart failure 5. Mechanisms of hypertrophy in heart failure 6. Hemodynamic adaptive mechanisms in heart failure 7. Neurohormonal axis and natriuretic peptides in heart failure 8. Novel biomarkers in heart failure 9. Systolic and diastolic function 10. Echocardiographic quantitation of ventricular function 11. MRI assessment of heart failure 12. Assessment of heart failure by invasive methods 13. The lymphatic system in heart failure 14. Endothelial dysfunction in heart failure in the child and young adult Section II Clinical diagnosis and management of pediatric heart failure 15. Epidemiology and economics of pediatric heart failure 16. Clinical recognition of heart failure in children 17. Classification of pediatric heart failure 18. Right ventricular dysfunction 19. Pediatric myocarditis 20. Dilated cardiomyopathy 21. Clinical features of restrictive cardiomyopathy and constrictive pericarditis 22. Hypertrophic cardiomyopathy 23. Left ventricular noncompaction cardiomyopathy 24. Arrhythmogenic cardiomyopathies 25. Valvular insufficiency and heart failure 26. Valvular stenosis and heart failure 27. Coronary artery disease in children and young adults 28. Chronic heart failure in congenital heart disease including single ventricle circulation 29. Heart failure in adults with congenital heart disease 30. Dysrhythmias and ventricular dysfunction and heart failure 31. Fetal heart failure 32. Heart failure in the neonate 33. Heart failure in pediatric pulmonary diseases 34. Pediatric cardiorenal syndrome 35. Heart failure in pediatric oncologic disease 36. Neuromuscular disorders 37. Sickle cell disease 38. The cardiovascular system in systemic inflammatory syndromes 39. Outpatient management of pediatric heart failure 40. Cardiac intensive care and inpatient management of heart failure 41.Quality of life, neurodevelopmental and psychosocial outcomes in pediatric heart failure 42. Palliative care 43. Quality metrics and quality improvement in pediatric heart failure 44. Nursing aspects of heart failure Section III Medical treatment for pediatric heart failure 45. Diuretic and invasive fluid management strategies 46. Inotropic agents in heart failure 47. Phosphodiesterase inhibitors 48. Use of vasodilators in heart failure 49. Recognition and treatment of low cardiac output states in pediatric cardiac intensive care 50. New therapeutic strategies for heart failure 51. Electrophysiologic devices in heart failure 52.Catheter device therapies for heart failure Section IV Cardiac surgery and pediatric heart failure 53. Posttransplant heart failure 54. Surgical strategies for the failing single ventricle 55. Valve interventions for heart failure 56. Principles of mechanical cardiopulmonary support 57. Future of mechanical circulatory support devices in children and young adults 58. Short-term mechanical cardiopulmo-nary support devices 59. Decision-making in ventricular assist device support in pediatric advanced heart failure patients 60. Long-term ventricular assist devices in children Section V Special topics 61. Genetics and genomics 62. Genetic testing 63. Big data and artificial intelligence in pediatric heart failure 64. Outpatient monitoring and self- care 65. Cardiac regenerative medicine for congenital heart defects 66. Development of digital twin models for heart failure patient treatment 67. Nutritional assessment and management in pediatric heart failure 68. The role of wearable technology in improving the care of pediatric heart failure


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Product Details
  • ISBN-13: 9780443132797
  • Publisher: Elsevier Science Publishing Co Inc
  • Publisher Imprint: Academic Press Inc
  • Height: 276 mm
  • No of Pages: 1030
  • Sub Title: From Bench to Bedside
  • Width: 216 mm
  • ISBN-10: 0443132798
  • Publisher Date: 27 Oct 2025
  • Binding: Paperback
  • Language: English
  • Returnable: Y
  • Weight: 2741 gr


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