Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 69. Chapters: Alcelaphine herpesvirus 2, Alloherpesviridae, Baboon lymphocryptovirus, Betaherpesvirinae, Bovine herpesvirus 1, Bovine herpesvirus 2, Bovine herpesvirus 5, Bovine malignant catarrhal fever, Canine herpesvirus, Channel catfish virus, Chickenpox, Chimpanzee lymphocryptovirus, Congenital cytomegalovirus infection, Duck plague, Epidemiology of herpes simplex, Epstein-Barr virus, Equine herpesvirus, Equine herpesvirus 1, Equine herpesvirus 2, Equine herpesvirus 3, Equine herpesvirus 4, Feline viral rhinotracheitis, Gallid herpesvirus 1, Gammaherpesvirinae, Haliotid herpesvirus 1, Herpesvirales, Herpesvirus gorilla, Herpes B virus, Herpes simplex virus, Herpes simplex virus protein vmw65, Herpes zoster, Herpetic whitlow, HHV capsid portal protein, HHV Infected Cell Polypeptide 0, HHV Latency Associated Transcript, HSUR, Human cytomegalovirus, Human herpesvirus 6, Human herpesvirus 7, Kaposi's sarcoma-associated herpesvirus, Malacoherpesviridae, Mardivirus, Marek's disease, Murid herpesvirus 4, Murid herpesvirus 68, Muromegalovirus, Orangutan lymphocryptovirus, Pseudorabies, Rhadinovirus, Rhesus lymphocryptovirus, Roseolovirus, Simian varicella virus, Varicella zoster virus, Varicellovirus, Viral tegument. Excerpt: Human herpesvirus 6 (HHV-6) is the common collective name for Human herpesvirus 6A (HHV-6A) and Human herpesvirus 6B (HHV-6B). These closely related viruses are two of the nine herpesviruses known to have humans as their primary host. HHV-6A and HHV-6B are double stranded DNA viruses within the betaherpesvirinae subfamily and of the genus Roseolovirus. HHV-6A and HHV-6B infects almost all of the human populations tested. HHV-6A has been described as more neurovirulent, and as such is more frequently found in patients with neuroinflammatory diseases such as multiple sclerosis. HHV-6B primary infection is the cause of the common childhood illness exanthem subitum (also known as roseola infantum or sixth disease). Additionally, HHV-6B reactivation is common in transplant recipients, which can cause several clinical manifestations such as encephalitis, bone marrow suppression and pneumonitis. A variety of tests have been used to detect HHV-6, some of which do not differentiate the species. Two types of infections have been described: active and inactive/latent infections. Histological slide of the human herpes virus-6 showing infected cells, with inclusion bodies in both the nucleus and the cytoplasm. The slide is stained with H&E.During 1986, Dharam Ablashi, Syed Zaki Salahuddin, and Robert Gallo cultivated peripheral blood mononuclear cells from patients with AIDS and lymphoproliferative illnesses. When they did, they found short-lived, large, refractile cells that frequently contained intranuclear and/or intracytoplasmic inclusion bodies. Electron microscopy revealed a novel virus that they named human B-lymphotrophic virus (HBLV). Shortly after its discovery, Ablashi et al. described five cell lines that can be infected by the newly discovered HBLV. They published that HSB-2, a particular T-cell line, was highly susceptible to infection. This pioneering research concluded by suggesting that the virus name be changed from HBLV to HHV-6, in accord with the published p