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Home > Biographies & Memoire > Biography and non-fiction prose > Biography: general > A Hidden Legacy: The Life and Work of Esther Zimmer Lederberg
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A Hidden Legacy: The Life and Work of Esther Zimmer Lederberg

A Hidden Legacy: The Life and Work of Esther Zimmer Lederberg

          
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About the Book

It's time to honor the significant scientific contributions of Esther Zimmer Lederberg. In A Hidden Legacy, Thomas E. Schindler shares the story of this remarkable microbiologist and offers insight into why her legacy has been obscured for so long. In the mid-20th century, microbiologist Esther Zimmer Lederberg and her then-husband, Joshua Lederberg, made a series of remarkable discoveries that contributed to the biochemical understanding of the gene. Together, they laid the foundation for molecular biology and the field of bacterial genetics. In 1958, he alone was awarded the Nobel Prize for their work. Esther's ingenuity was largely ignored and undervalued by the Nobel committee and has continued to be obscured by historians of science. In this book, Thomas E. Schindler shares many of Esther's hidden scientific contributions and her role in the discoveries that launched her then-husband's celebrated career. A Hidden Legacy delves into how, as a couple, the Lederbergs established a new field of bacterial genetics in the decade leading up to the discovery of the DNA double helix. Their impressive series of achievements includes the discovery of: *l bacteriophage and the first plasmid, known as the F-factor; how viruses carry bacterial genes between bacteria; and fundamental properties of bacterial sex. Schindler explains how Esther's research revealed unique features of bacterial sex that are now essential to our understanding of molecular biology and evolution. A magnificent story of a remarkable scientist, A Hidden Legacy takes readers through the process that scrambled the tree of life and offers insight into the role Esther played in uncovering these secretes of bacterial and viral genes.

Table of Contents:
Introduction Chapter 1: An Abiding Affection Chapter 2: The Pathway to Bacterial Genetics Chapter 3: Graduate School: Mentored by the Future Nobel Laureates, George Beadle and Edward Tatum Chapter 4: The Anomaly of Bacterial Genetics Chapter 5: Love in the Laboratory: A Marriage of Two Prodigies Chapter 6: Strange Genetics: Bacterial Genes Move Sideways Chapter 7: Clarifying the Unique Features of Bacterial Sex Chapter 8: Replica Plating: Esther Repurposes Her Compact Makeup Sponge Chapter 9: The Matilda Effect: Joshua Lederberg's Brilliance Obscured His Wife's Reputation Chapter 10: What She Did for Love: Demoted from Research Collaborator to Nobel Wife Chapter 11: Behind the Laboratory Doors: For Over One Hundred Years of Science, Women Participated in Obscurity Chapter 12: Antibiotic Resistance, the Horrendous Consequences of Bacterial Sex Chapter 13: The Lederbergs' Stanford Years, 1959-1976: Growing Apart, the Collaborative Couple Divorce Chapter 14: The Central Importance of E. coli and λ Phage in the New Molecular Biology Chapter 15: Making Music and a New Life Epilogue: A New Tree of Life and a New Concept for the Gene Acknowledgments Index


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Product Details
  • ISBN-13: 9780197531679
  • Publisher: Oxford University Press Inc
  • Publisher Imprint: Oxford University Press Inc
  • Height: 162 mm
  • No of Pages: 176
  • Spine Width: 20 mm
  • Weight: 390 gr
  • ISBN-10: 0197531679
  • Publisher Date: 20 Oct 2021
  • Binding: Hardback
  • Language: English
  • Returnable: Y
  • Sub Title: The Life and Work of Esther Zimmer Lederberg
  • Width: 246 mm


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