This comprehensive volume offers a cutting-edge examination of high-throughput and label-free analysis techniques, showcasing their transformative impact on biomedical, pharmaceutical, and materials research. By bridging historical context with the latest technological advances, the book provides a detailed overview of how high-throughput screening (HTS)—once limited to synthetic compound assays—has evolved into a powerful, label-free platform capable of probing biological phenomena at the single-cell and single-molecule level. The topics span from surface plasmon resonance, hyperspectral imaging, and single-molecule electronics to regenerative tissue engineering and organoid development, culminating in discussions on soft, bio-integrated electronics for real-time monitoring. Each chapter integrates fundamental principles with applied research, providing readers with a panoramic view of how HTS technologies are being redefined across various domains. The book serves as a crucial reference for the next generation of bioanalytical and nanotechnology tools driving innovation in diagnostics, drug discovery, and tissue engineering and is ideal for researchers, industry scientists, graduate students, and anyone eager to engage with this rapidly evolving field.
This book provides a unified resource on emerging label-free and high-throughput techniques, which are crucial for next-gen diagnostics, drug development, and tissue modeling. It bridges the gap between traditional assays and modern, real-time, non-invasive analyses that are critical for precision medicine.
Table of Contents:
Chapter 1 High-Throughput and Label-Free Analysis Mahima Gupta, Sreyashi Das, and Ram V. Devireddy Chapter 2 High-Throughput Analysis of Stem Cells Mohan K. Dey, Sreyashi Das, Kirti Agrawal, Ram V. Devireddy, and Manas R. Gartia Chapter 3 High-Throughput Detection Approaches Based on Surface Plasmon Resonance Fenni Zhang, Jinbiao Ma, Xiaoyin Liu, Jiahao Xu, Yanli Lu, and Qingjun Liu Chapter 4 Hyperspectral Imaging of Optically Resonant Surfaces for Multiplexed Sensing of Biomaterials Qinming Zhang, Shirin Parvin, Liang Dong, and Meng Lu Chapter 5 Single-Molecule Junctions for Electrical Detection of Biomolecules Ian Bunker and Kun Wang Chapter 6 Tissue Engineering Approach: 3D Printing Mahima Gupta and Ram V. Devireddy Chapter 7 Organoids: In Vitro Alternatives to Study In Vivo Events and the Possibility of Using 3D Bioprinting and Hyperspectral Imaging for Better Outcomes Saumya Rai, Mohankumar B. S., Qudsiya Mohiuddin, Bhawana, Sanya Sharma, and Santosh K. Misra Chapter 8 Integration of Electronics with Biological Systems Anish Maharjan, Julio Zuazola, and Robert Herbert
