Part of the popular High-Yield™ Series , this updated Third Edition provides a succinct, heavily illustrated review in outline format of medical biochemistry for students preparing for USMLE Step 1. Highlights of this edition include revised and updated chapters on gene expression and biomedical technology. More clinical correlates have been added throughout the text.

Table of Contents:
Preface Acknowledgments 1 Acid-Base Relationships I.Acidic dissociation II.Measures of acidity III.Buffers IV.Acid-base balance V.Acid-base disorders VI.Clinical relevance: diabetic ketoacidosis 2 Amino Acids and Proteins I.Functions of proteins II.Proteins as polypeptides III.Protein structure IV.Protein solubility and R-groups V.Protein denaturation VI.Clinical relevance 3 Enzymes I.Energy relationships II. Free-energy change III.Enzymes as biological catalysts IV. Michaelis-Menten equation V. Lineweaver-Burk equation VI.Enzyme regulation VII.Clinical relevance: methanol and ethylene glycol poisoning 4 Citric Acid Cycle and Oxidative Phosphorylation I.Cellular energy and adenosine triphosphate II.Citric acid cycle III.Products of the citric acid cycle (one revolution) IV.Synthetic function of the citric acid cycle V.Regulation of the citric acid cycle VI.Electron transport and oxidative phosphorylation VII.Chemiosmotic hypothesis VIII.Clinical relevance 5 Carbohydrate Metabolism I.Carbohydrate digestion and absorption II.Glycogen metabolism III. Glycolysis IV.Gluconeogenesis V.Regulation of glycolysis and gluconeogenesis VI.Pentose phosphate pathway VII.Sucrose and lactose metaboli sm VIII.Clinical relevance 6 Lipid Metabolism I.Lipid function II.Lipid digestion III.Lipoprotein transport and metabolism IV.Oxidation of fatty acids V.Fatty acid synthesis VI.Glycerolipid synthesis VII.Sphingolipid synthesis VIII.Cholesterol synthesis IX. Clinical relevance 7 Amino Acid Metabolism I. Functions of amino acids II.Removal of amino acid nitrogen III.Urea cycle and detoxification of NH+ IV.Carbon skeletons of amino acids V.Clinical relevance: inherited (inborn) errors of amino acid metabolism 8 Nucleotide Metabolism I.Nucleotide structure II.Nucleotide function III. Purine nucleotide synthesis IV.Pyrimidine nucleotide synthesis V.Deoxyribonucleotide synthesis VI.Nucleotide degradation VII.Clinical relevance 9 Nutrition I.Energy needs II.Macronutrients III.Micronutrients: the fat-soluble vitamins IV.Micronutrients: the water-soluble vitamins V.Minerals 10 Gene Expression I.Genetic information II.DNA and RNA: nucleic acid structure III.DNA synthesis (replication) IV.Transcription V.Translation (protein synthesis) VI.Mutations 11 Biochemical Technology I.Protein purification II.Protein analysis III.DNA analysis IV.Cloning of recombinant DNA and protein V.Clinical relevance 12 Hormones I.Overview II.Classification of hormones III.Mechanisms of hormone action IV.Hormones that regulate fuel metabolism V.Hormones that regulate salt and water balance VI.Hormones that regulate calcium and phosphate metabolism VII.Hormones that regulate body size and metabolism VIII.Hormones that regulate the male reproductive system abbreviated Table of Contents"