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Human Drug Kinetics: A Course of Simulated Experiments

Human Drug Kinetics: A Course of Simulated Experiments

          
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About the Book

"Human Drug Kinetics" is a teaching course contained in a self-sufficient text and based on experiments simulated by students using the sophisticated software provided for IBM PC-compatible microcomputers. The book and software are available as a self-contained package and copies of the book are also available separately. "Human Drug Kinetics" will provide either a short complete course or complementary experiment simulations for existing courses. The book is more than a manual for the software component of the course. It provides the background and theory necessary for students to understand fully the simulations provided in the software. It also helps teachers to place the package sensibly and relevantly in the courses that they are teaching. This teaching course is derived from 20 years experience gained in collaboration between McMaster University, the London School of Pharmacy and St Bartholomew's Hospital. The authors provide a comprehensive educational tool. The pharmacokinetic model on which the simulations are built uses the experience gained in developing the well-known MacDope model.

Table of Contents:
Drug kinetic theory; Single intravenous dose experiments to determine pharmacokinetic parameters; Single oral and intramuscular dose experiments to determine; Operational details form the simulation model; Continuous and multiple dosing regiments, intravenous and oral doses; Multiple dosing regiments, sustained - release oral and intramuscular; Capacity-limited metabolism and repeated dosing. Studies with phenytoin enzyme kinetics and metabolic reactions; Pharmacokinetics in disease states. Studies with Paracetamol and Gentamycin; Doses, response and regiments with different subject. Studies with Temazapam, Paracetamol, Phenytoin and Digoxin.


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Product Details
  • ISBN-13: 9780199630387
  • Publisher: Oxford University Press
  • Publisher Imprint: Oxford University Press
  • Height: 235 mm
  • Returnable: N
  • Weight: 630 gr
  • ISBN-10: 0199630380
  • Publisher Date: 30 Jun 1989
  • Binding: Hardback
  • Language: English
  • Sub Title: A Course of Simulated Experiments
  • Width: 155 mm


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