Home > Medicine & Health Science textbooks > Pre-clinical medicine: basic sciences > Physiology > The Hypertrophied Heart: Biophysical, biochemical, and morphological aspects of hypertrophy. International Erwin Riesch Symposium,Tübingen, September 26–29, 1976(German)
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The Hypertrophied Heart: Biophysical, biochemical, and morphological aspects of hypertrophy. International Erwin Riesch Symposium,Tübingen, September 26–29, 1976(German)

The Hypertrophied Heart: Biophysical, biochemical, and morphological aspects of hypertrophy. International Erwin Riesch Symposium,Tübingen, September 26–29, 1976(German)

          
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About the Book

Die Umkehr der Calcium-Pumpe des myokardialen sarkoplasmatischen Retikulums (SR) wurde untersucht. SR-Vesikel, die passiv durch Prliinkubation mit hohen Calciumkonzentrationen mit Calcium beladen wurden, synthetisieren ATP aus Orthophosphat und ADP. Die ATP-Synthese erfolgt tiber die Phos- phorylierung der Calcium-Transport-ATPase des SR durch Orthophosphat und eine Dephosphorylierung des E '""" P durch ADP. Die Rate der Calcium-Frei- setzung aus SR-Vesikel - die Calcium-Beladung erfolgte aktiv in Gegenwart von Acetylphosphat - wird durch ADP erhoht. Der ADP-abhlingige Calcium- Efflux ist stochiometrisch mit der ATP-Synthese aus Orthophosphat und ADP gekoppelt. References 1. Suko, J.: The calcium pump of cardiac sarcoplasmic reticulum. Functional alterations at different levels of thyroid state in rabbits. J. Physiol. 228, 563 (1973). 2. Hasselbach, W.: Sarcoplasmic Membrane. ATPase. In: The Enzymes (P. D. Boyer, eds.), N. Y. 10, 431 (1974). 3. Pang, D. C., N. F. Briggs: Reaction mechanism of cardiac sarcotuble calcium dependent adenosin triphosphatase. Biochemistry 12, 4905 (1973). 4. Suko, J., W. Hasselbach: Properties of a phosphorylated intermediate of the 2 Ca -dependent ATPase and ADP-ATP phosphate exchange of cardiac sarco- plasmic reticulum. Naunyn-Schmiedeberg's Arch. Pharmakol. expo Pathol. 282, R. 97 (1974). 5. Suko, J., W. Hasselbach: Characterization of cardiac sarcoplasmic reticulum ATP-ADP phosphate exchange and phosphorylation of the calcium trans- port adenosin triphosphatase. Europ. J. Biochem. 64, 123 (1976). 2 2 6. Suko, J.: The effect of temperature on Ca +-uptake and Ca +-activated ATP hydrolysis by cardiac sarcoplasmic reticulum. Experientia 29, 396 (1973).

Table of Contents:
Preface.- The instantaneous force-velocity relationship as an index of the contractile state in cardiac muscle / Die momentane Kraft-Geschwindigkeit-Beziehung als ein Index für den kontraktilen Status des Herzmuskels.- The effect of preload and Ca++-ions on the time-course of the isometric force and on the force-velocity re­lation: Is Vmax dependent on the number of activated cross-bridges? / Der Einfluß von Vorbelastung und Ca++-Ionen auf den Zeitverlauf der isometrischen Kraft und auf die Kraft-Geschwindigkeit-Beziehung: Hängt Vmax von der Zahl aktivierter Querbrücken ab?.- Molecular aspects of muscle contraction and regulation / Molekulare Aspekte der Muskelkontraktion und Erschlaffung.- Regulation of actin-myosin interaction / Regulation der Aktin-Myosin-Interaktion.- Evidence for head-head interactions in myosin from cardiac and skeletal muscles / Wechselwirkungen zwischen den beiden Köpfen in Myosin aus Herz- und Skelettmuskeln.- Ca++ activation of ATPase activity, ATP-Pi exchange, and tension in briefly glycerinated heart muscle / Ca++-Aktivierung von ATPase-Aktivität, ATP-Phosphat-Austausch und Kontraktionskraft in glycerinextrahierten Herzmuskelfasern.- Elementary events in excitation-contraction coupling of the mammalian myocardium / Grundprozesse der elektro-mechanischen Kopplung im Säugetiermyo­kard.- The reversal of the calcium pump of cardiac sarcoplasmic reticulum / Die Umkehr der Calcium-Pumpe des myokardialen sarkoplasmatischen Retikulums.- The partitioning of altered mechanics in hypertrophied heart muscle between the sarcoplasmic re­ticulum and the contractile apparatus by means of myothermal measure­ments / Zuordnung einer veränderten Mechanik beim hypertrophierten Herzen zu sarkoplasmatischem Retikulum und kontraktilem Apparat auf derGrundlage von Messungen der Muskelwärme.- Myocardial function in different models of cardiac hypertrophy. An attempt at correlating mechanical, bio­chemical, and morphological parameters / Myokardfunktion bei verschiedenen Modellen der Herzhypertrophie. Versuch einer Korrelation mechanischer, biochemischer und morphologi­scher Parameter.- Analytical approach to mathematical modelling of the isometric contraction of the hypertrophied myocardium / Ein mathematisches Modell zur näherungsweisen Berechnung des iso­metrischen Zuckungsverlaufs beim hypertrophierten Myokard.- Cardiac function in the chronically volume-overloaded canine heart / Experimentelle Untersuchungen zur Funktion des chronisch volumen­belasteten Herzens.- Dynamics of the hypertrophied left ventricle in the rat. Effects of physical train­ing and chronic pressure load / Die Dynamik des hypertrophierten linken Ventrikels der Ratte. Einfluß von körperlichem Training und chronischer Druckbelastung.- Effects of hypertrophy on con­tractile function in man / Auswirkungen der Hypertrophie auf die kontraktile Herzfunktion beim Menschen.- Dynamic geometry of the left ventricle in hypertrophy studied by quantitative angiocardiography / Quantitative angiokardiographische Studien über die dynamische Geo­metrie des hypertrophierten linken Ventrikels.- Cellular changes in mechanically overloaded heart / Zelluläre Veränderungen im mechanisch überbelasteten Herzen.- Myocardial hypertrophy. Light microscopic findings on the myocardium. Blood supply. Ventricular dilatation and heart failure / Herzhypertrophie. Lichtmikroskopische Befunde am Myokard. Blutver­sorgung. Herzdilatation und Herzversagen.- Time course of electron microscopic alterations in the hypertrophied myocardium of Goldblatt rats / ZeitlicherVerlauf elektronenmikroskopischer Veränderungen beim hy­pertrophierten Myokard von Goldblattratten.- Experimental studies on cardiac muscle cell adaptation to insult / Untersuchungen über Anpassungserscheinungen an Herzmuskelzellen bei experimenteller Schädigung.- Hypertrophy due to chronic volume overloading in the dog heart. A morphometric study / Hypertrophie nach chronischer Volumenübertragung am Hundeherzen. Eine morphometrische Untersuchung.- The common mechanism of the heart’s adaptation and deadaptation: hypertrophy and atrophy of the heart muscle / Hypertrophie und Atrophie des Herzmuskels als Anpassungsmechanismen.- Metabolism of myofibrillar proteins in the normal and hypertrophic heart / Stoffwechsel der myotbrillären Proteine in normalen und hyertrophier­ten Herzen.- Changes of myocardial adenine nucleotide and protein synthesis during development of cardiac hypertrophy / Veränderungen der myokardialen Adenin-Nucleotid- und Proteinsyn­these während der Entwicklung der Herzhypertrophie.- Transformation of mor­phological, functional and metabolic properties of fast-twitch muscle as induced by long-term electrical stimulation / Transformation morphologischer, funktioneller und metabolischer Eigen­schaften schneller Muskeln durch langdauernde elektrische Reizung.- Cardiac myosin. Phylogenic and pathological changes / Herzmuskel-Myosin. Phylogenetische und pathologische Veränderungen.- Characteristics of the hypertrophied left ventricular myocardium in Goldblatt rats / Eigenschaften des hypertrophierten linken Ventrikels in Goldblatt-Ratten.- The role of Ca++ ions in the hypertrophied myocardium / Der Kalziumstoffwechsel im hypertrophierten Myokard.- The intracellular pH and the buffer capacity of the heart / Das intrazelluläre pH und diePufferkapazität des Herzens.- Restriction of ?-adrenergic re­sponsiveness in hypertrophied ventricular myocardium of rats / Einschränkung der ?-adrenergen Ansprechbarkeit im hypertrophierten Rattenmyokard.- Transmural distribution of myocardial blood flow and of coronary re­serve in canine left ventricular hypertrophy / Transmurale Verteilung der Myokarddurchblutung und der Koronar­reserve in Hunden mit Hypertrophie des linken Ventrikels.- Myocardial oxygen consumption and substrate uptake in man during physiological and pathological volume load / Myokardialer Sauerstoffverbrauch und Substrataufnahme beim Men­schen während physiologischer und pathologischer Volumenbelastung.- Influences on the efficiency of cardiac work / Einflüsse auf den Nutzeffekt der Herzarbeit.- Left ventricular systolic wall stress as a primary determinant of myo­cardial oxygen consumption: Comparative studies in patients with nor­mal left ventricular function, with pressure and volume overload and with coronary heart disease / Vergleichende Untersuchungen über die Beziehungen zwischen der Ven­trikelfunktion, Kontraktilität und maximalen systolischen Wandspan­nung sowie dem Sauerstoffverbrauch des linken Ventrikels bei Patien­tengruppen mit Normalfunktion, chronischer Druck- und Volumenbe­lastung und koronarer Herzkrankheit.


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Product Details
  • ISBN-13: 9783798504820
  • Publisher: Steinkopff Darmstadt
  • Publisher Imprint: Steinkopff Darmstadt
  • Height: 244 mm
  • No of Pages: 222
  • Series Title: German
  • Sub Title: Biophysical, biochemical, and morphological aspects of hypertrophy. International Erwin Riesch Symposium,Tübingen, September 26–29, 1976
  • Width: 170 mm
  • ISBN-10: 3798504822
  • Publisher Date: 01 Jan 1977
  • Binding: Paperback
  • Language: German
  • Returnable: Y
  • Spine Width: 12 mm
  • Weight: 376 gr


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The Hypertrophied Heart: Biophysical, biochemical, and morphological aspects of hypertrophy. International Erwin Riesch Symposium,Tübingen, September 26–29, 1976(German)
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