Expert guidance from internationally recognized authorities, who provide clear and current updates on all aspects of interventional cardiology. This new edition; Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more  Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book  Features 19 procedural videos, hosted on a companion website

Table of Contents:
About the Companion Website   vi Contributors   vii Foreword   xvi Preface   xvii Acknowledgments   xviii Part I Principles and Techniques   1 Section I Basic Knowledge  3 1 Atherogenesis and Inflammation    3 Umair Hayat, Vikas Thondapu, Tim Tsay, and Peter Barlis 2 The Essentials of Femoral Vascular Access and Closure   17 Ted Feldman and Mohammad Sarraf 3 Radial Artery, Alternative Arm Access, and Related Techniques   27 Thomas J. Ford, Martin K.C. Ng, Vikas Thondapu, and Peter Barlis 4 Optimal Angiographic Views for Coronary Angioplasty   34 Gioel Gabrio Secco and Carlo Di Mario 5 Material Selection   44 Sahil A. Parikh, Michele Pighi, and Carlo Di Mario Section II  Imaging and Physiology    59 6 Physiologic Assessment in the Cardiac Catheterization Laboratory: CFR, FFR, iFR, and Beyond   59 Sukhjinder Nijjer and Justin Davies 7 Intravascular Ultrasound and Virtual Histology: Principles, Image Interpretation, and Clinical Applications    71 Adriano Caixeta, Akiko Maehara, and Gary S. Mintz 8 Optical Coherence Tomography, Near-Infrared Spectroscopy, and Near-Infrared Fluorescence Molecular Imaging    91 Ismail Dogu Kilic, Roberta Serdoz, Enrico Fabris, Farouc Amin Jaffer, and Carlo Di Mario 9 Complementary Imaging Techniques: Multislice Computed Tomography of Coronary Arteries    107 Omosalewa O. Lalude, Francesca Pugliese, Pim J. de Feyter, and Stamatios Lerakis 10 Cardiovascular Magnetic Resonance Imaging   126 Omosalewa O. Lalude and Stamatios Lerakis Section III PCI in Different Clinical Settings  138 11 Stable Coronary Artery Disease   138 Abhiram Prasad and Bernard J. Gersh 12 PCI Strategies in Acute Coronary Syndromes without ST Segment Elevation (NSTEACS)   148 Georgios E. Christakopoulos, Subhash Banerjee, and Emmanouil S. Brilakis 13 Primary and Rescue PCI in Acute Myocardial Infarction and Elements of Myocardial Conditioning    155 Tayo Addo, Neil Swanson, and Anthony Gershlick 14 The Management of Cardiogenic Shock and Hemodynamic Support Devices and Techniques   163 Bimmer E.P.M. Claessen, Dagmar Ouweneel, and José P.S. Henriques Section IV PCI in Different Lesion Types   168 15 Percutaneous Coronary Intervention in Unprotected Left Main  168 Gill Louise Buchanan, Alaide Chieffo, and Antonio Colombo 16 Bifurcation Lesion Stenting   175 Yves Louvard, Thierry Lefevre, Bernard Chevalier, and Philippe Garot 17 Risk Stratification Approach to Multivessel Coronary Artery Disease   185 Davide Capodanno and Corrado Tamburino 18 Chronic Total Coronary Occlusion    190 Gerald S. Werner and Emmanouil S. Brilakis 19 Percutaneous Coronary Intervention of Arterial and Vein Grafts   201 Bimmer E.P.M. Claessen, José P.S. Henriques, and George D. Dangas 20 Interventional Approach in Small Vessel, Diffuse, and Tortuous Coronary Artery Disease    205 Robert Pyo 21 In-Stent Restenosis in New Generation DES Era   213 Marco G. Mennuni and Patrizia Presbitero Section V Special Techniques and Complications    224 22 Laser, Rotational, and Orbital Coronary Atherectomy   224 Kaleab N. Asrress, Peter O’Kane, Robert Pyo, and Simon R. Redwood 23 Thrombus-Containing Lesions    233 Giovanni Luigi De Maria and Adrian P. Banning 24 Specialized Balloons in Percutaneous Coronary Intervention: Cutting, Scoring, Gliding, and Drug-Eluting Balloons   244 Bimmer E.P.M. Claessen, José P.S. Henriques, and George D. Dangas 25 Coronary Artery Dissections, Perforations, and the No-Reflow Phenomenon    248 Adriano Caixeta, Luiz Fernando Ybarra, Azeem Latib, Flavio Airoldi, Roxana Mehran, and George D. Dangas 26 Access Site Complications   267 Jose M. Wiley, Fernando Pastor, and Cristina Sanina 27 Renal Insufficiency and the Impact of Contrast Agents    274 Michael Donahue and Carlo Briguori 28 Radiation Management in Interventional Cardiology    282 Stephen Balter and Charles E. Chambers 29 Concepts of Cell Therapy and Myocardial Regeneration    290 Kevin O’Gallagher, Zoë Astroulakis, Alex Sirker, and Jonathan M. Hill Section VI Clinical Trials in Coronary Heart Disease  296 30 Statistical Essentials in the Design and Analysis of Clinical Trials   296 Usman Baber and Stuart J. Pocock 31 Historical Perspective of Sirolimus and Paclitaxel-Eluting Stent Clinical Studies   301 Adriano Caixeta, Leonardo Guimarães, Philippe Généreux, and George D. Dangas 32 Cobalt-Chromium Everolimus-Eluting Stents    313 Vikas Thondapu, Yoshinobu Onuma, Bimmer E.P.M. Claessen, Patrick W. Serruys, and Peter Barlis 33 Platinum-Chromium Everolimus-Eluting Stents    326 Vikas Thondapu, Bimmer E.P.M. Claessen, George D. Dangas, Patrick W. Serruys, and Peter Barlis 34 Bioresorbable Stents   335 Gianluca Caiazzo, Alessio Mattesini, Ciro Indolfi, and Carlo Di Mario 35 The Biolimus Stent Family   344 Anna Franzone, Raffaele Piccolo, and Stephan Windecker 36 The Biotronik Stent Family   360 Anna Franzone, Raffaele Piccolo, and Stephan Windecker 37 Novel Drug-Eluting Stent Systems   368 J. Ribamar Costa, Jr., Adriano Caixeta, and Alexandre A.C. Abizaid Part II Interventional Pharmacology   377 Section I Fundamentals of Interventional Pharmacology  379 38 Basics of Antiplatelet and Anticoagulant Therapy for Cardiovascular Disease   379 Piera Capranzano and Dominick J. Angiolillo 39 Balance of Ischemia and Bleeding in Selecting Antithrombotic Regimens    389 Bimmer E.P.M. Claessen and José P.S. Henriques Section II  Pharmacological Agents    397 40 Oral Antiplatelet Agents in PCI   397 Jonathan A. Batty, Joseph R. Dunford, George D. Dangas, and Vijay Kunadian 41 Parenteral Anticoagulant Agents in PCI    408 Piera Capranzano, Corrado Tamburino, and George D. Dangas 42 Parenteral Antiplatelet Agents in PCI    415 Piera Capranzano, Giuseppe Gargiulo, and Corrado Tamburino 43 Role of Parenteral Agents in PCI for Stable Patients   421 Joanna Ghobrial, David A. Burke, and Duane S. Pinto 44 Vasoactive and Antiarrhythmic Drugs During PCI  432 Bimmer E.P.M. Claessen and José P.S. Henriques 45 The Optimal Duration of Dual Antiplatelet Therapy After PCI   436 Mikkel Malby Schoos, Roxana Mehran, and George D. Dangas 46 Triple Antiplatelet Therapy and Combinations with Oral Anticoagulants After PCI   443 Jonathan A. Batty, Joseph R. Dunford, Roxana Mehran, and Vijay Kunadian Section III Pharmacological Testing    453 47 Peri-procedural Platelet Function Testing in Risk Stratification and Clinical Decision Making   453 Paul A. Gurbel, Fang Liu, Gailing Chen, and Udaya S. Tantry 48 Genetics and Pharmacogenetics in Interventional Cardiology   459 Hillary Johnston-Cox, Johan L.M. Björkegren, and Jason C. Kovacic 49 Monitoring and Reversal of Anticoagulation and Antiplatelet Agents   469 Gregory W. Yost and Steven R. Steinhubl Part III Hypertension and Structural Heart Disease  485 Section I Systemic and Pulmonary Hypertension  487 50 Right Heart Catheterization and Pulmonary Hemodynamics  487 P. Christian Schulze 51 Treatment of Pulmonary Embolism: Medical, Surgical, and Percutaneous   491 Ian del Conde and Barry T. Katzen 52 Renal Denervation for Resistant Hypertension    499 Hitesh C. Patel, Carl Hayward, Sebastian Ewen, and Felix Mahfoud Section II Structural Heart Interventions   507 53 Antithrombotic Strategies in Valvular and Structural Heart Disease Interventions  507 Mikkel Malby Schoos, Davide Capodanno, and George D. Dangas 54 Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy    517 Amir-Ali Fassa, George D. Dangas, and Ulrich Sigwart 55 Left Atrial Appendage Exclusion   525 Jorge G. Panizo and Jacob S. Koruth 56 Cryptogenic Stroke, Patent Foramen Ovale, and ASD Closure   530 Barry Love 57 Paravalvular Leak Closure and Ventricular Septal Defect Closure   540 Saurabh Sanon, Mackram F. Eleid, Allison K. Cabalka, and Charanjit S. Rihal Section III Valvular Heart Disease Interventions   546 58 Aortic Valvuloplasty and Large-Bore Percutaneous Arterial Access   546 Matthew I. Tomey, Annapoorna S. Kini, Samin K. Sharma, and Jason C. Kovacic 59 Transfemoral Aortic Valve Implantation: Preparation, Implantation, and Complications    558 Brandon M. Jones, Samir R. Kapadia, Amar Krishnaswamy, Stephanie Mick, and E. Murat Tuzcu 60 Transthoracic Aortic Valve Implantation    569 Giuseppe Bruschi, Kaleab N. Asrress, Paola Colombo, and Vinayak N. Bapat 61 New Aortic Valve Technologies   575 Dimytri Alexandre Siqueira and Alexandre A.C. Abizaid 62 Transseptal Puncture    582 Alec Vahanian, Dominique Himbert, Fabrice Extramiana, Gregory Ducrocq, and Eric Brochet 63 Principles of Carpentier’s Reconstructive Surgery in Degenerative Mitral Valve Disease   592 Farzan Filsoufi and Alain Carpentier 64 Mitral Valve Repair: MitraClip and Emerging Techniques   599 Ted Feldman, Mohammad Sarraf, Mayra Guerrero, and Francesco Maisano 65 Balloon Mitral Valvuloplasty   606 C.N. Manjunath, Nagaraja Moorthy, and Upendra Kaul 66 Pulmonary Artery and Valve Catheter-Based Interventions    619 Kasey Chaszczewski, Damien Kenny,  and Ziyad M. Hijazi 67 Imaging for Planning and Guidance for Structural Heart Interventions   629 Ankit Parikh and Stamatios Lerakis Part IV Vascular Disease for the Interventionalist   641 Section I Cerebrovascular Disease   643 68 Acute Stroke Intervention    643 Stefan C. Bertog, Iris Q. Grunwald, Anna Luisa Kühn, Laura Vaskelyte, Ilona Hofmann, Sameer Gafoor, Markus Reinartz, Predrag Matic, and Horst Sievert 69 Carotid Artery Angioplasty and Stenting    653 Alberto Cremonesi, Shane Gieowarsingh, and Fausto Castriota 70 Cerebral Aneurysms: Diagnosis, Indications, and Strategies for Endovascular Treatment    671 Gyula Gál Section II Aorta and Branch Diseases   677 71 Management of Acute Aortic Syndromes   677 Christoph A. Nienaber and Rachel E. Clough 72 Thoracic Endovascular Aortic Aneurysm Repair   687 Paul S. Lajos and Michael L. Marin 73 Endovascular Aortic Aneurysm Repair   692 William Beckerman, Paul S. Lajos, and Peter L. Faries 74 Acute and Chronic Mesenteric Ischemia    698 Robert J. Rosen, Amit Jain, and Jennifer Drury 75 Renal Artery Interventions    705 Mark Shipeng Yu, Kun Xiang, Steven T. Haller, and Christopher J. Cooper 76 Revascularization for Arteries in the Pelvis   713 Femi Philip and Jason H. Rogers Section III Peripheral Arterial Disease  721 77 Iliac Interventions    721 Manish Taneja and Apoorva Gogna 78 Superficial Femoral Artery Interventions    726 Cristina Sanina, Pedro R. Cox-Alomar, Prakash Krishnan, and Jose M. Wiley 79 Popliteal Artery Interventions    733 Karthik Gujja, Gopi Punukollu, Vishal Kapur, and Prakash Krishnan 80 Below the Knee Interventions in Critical Limb Ischemia   738 Karthik Gujja, Katarzyna Nasiadko, Arthur Tarricone, and Prakash Krishnan 81 Subclavian, Vertebral, and Upper Extremity Vascular Disease   748 Ian Del Conde, Cristina Sanina, and Jose M. Wiley Section IV Venous Disease/Interventions  754 82 Antithrombotic Strategies in Endovascular Interventions: Current Status and Future Directions   754 Mehdi H. Shishehbor 83 Chronic Venous Insufficiency   759 Karthik Gujja, Cristina Sanina, and Jose M. Wiley 84 Cardiac Vein Anatomy and Transcoronary Sinus Catheter Interventions in Myocardial Ischemia  768 Werner Mohl, Levente Molnár, and Béla Merkely Index   776