Interventions to Improve Antimalarial Use: v. 76, 1998

Interventions to Improve Antimalarial Use: v. 76, 1998

          
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About the Book

A collection of eight research projects derived from a report aimed at identifying and testing ways to rationalize and improve the home treatment of malaria using existing oral antimalarials. Malaria experts involved in the project were unanimous in the view that increased benefits from antimalarials could best be achieved by focusing on improving drug quality, prescribing practices, and patient compliance with full multidose drug combinations or monotherapy. Research interventions were implemented in six South-East Asian countries - Cambodia, China, Lao People's Democratic Republic, Myanmar, Thailand and Vietnam - known to have the highest rates of antimalarial multidrug resistance in the world. Treatment regimens included a five-day combination of artesunate and mefloquine and a seven-day course of quinine and tetracycline. Research was designed to test the effect of small but potentially important changes in the delivery of drugs in the private sector. Approaches tested and reported in this special supplement to the "Bulletin of the World Health Organization" include the introduction of a subsidized system for providing combination drugs for treatment, improved packaging of doses with compartments for each day's treatment, use of new dose-specific blister packs, health education interventions, use of a pharmacological marker to measure compliance, and assessment of drug quality. User-friendly packaging of drugs, which include simple but important information for patients, produced the best results in terms of improving treatment compliance. Research also found alarming problems with drug quality, with all antimalarials randomly collected from endemic areas showing an unacceptably low drug content.


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Product Details
  • ISBN-13: 9789240687516
  • Publisher: World Health Organization
  • Publisher Imprint: World Health Organization
  • Edition: Illustrated edition
  • Sub Title: v. 76, 1998
  • Width: 160 mm
  • ISBN-10: 9240687513
  • Publisher Date: 01 Aug 1998
  • Binding: Paperback
  • Height: 240 mm
  • Weight: 17 gr


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