Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Neurology and clinical neurophysiology > Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology(English)
55%
Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology(English)

Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology(English)

          
5
4
3
2
1

Available


Premium quality
Premium quality
Bookswagon upholds the quality by delivering untarnished books. Quality, services and satisfaction are everything for us!
Easy Return
Easy return
Not satisfied with this product! Keep it in original condition and packaging to avail easy return policy.
Certified product
Certified product
First impression is the last impression! Address the book’s certification page, ISBN, publisher’s name, copyright page and print quality.
Secure Checkout
Secure checkout
Security at its finest! Login, browse, purchase and pay, every step is safe and secured.
Money back guarantee
Money-back guarantee:
It’s all about customers! For any kind of bad experience with the product, get your actual amount back after returning the product.
On time delivery
On-time delivery
At your doorstep on time! Get this book delivered without any delay.
Add to Wishlist

About the Book

The blood-brain barrier serves to protect the brain from toxic substances whilst simultaneously allowing access to essential nutrients and chemical signals. At the interface between brain and body, knowledge of the blood-brain barrier forms an essential component in the complete understanding of a large proportion of medical disciplines. Nevertheless, it seems that ignorance of both the biology of this important membrane and the methodology suitable for its investigation still remains an impediment to progress in many fields, including, for example, the development of new and efficacious neuropharmaceuticals, cerebrovascular disease, Alzheimer's disease, cerebral AIDS and brain tumours. This introduction for both researchers and clinicians across the medical sciences is intended to aid both those beginning work directly in this area and those wishing simply to be better informed when interpreting information where the blood-brain barrier may be involved. Advances in both methodology and biology are detailed in 50 chapters from international authorities.

Table of Contents:
List of contributors; 1. Blood-brain barrier methodology and biology; Part I. Methodology: 2. The carotid artery single injection technique; 3. Development of the Brain Efflux Index (BEI) method and its application to the blood-brain barrier efflux transport study; 4. In situ brain perfusion; 5. Intravenous injection/pharmacokinetics; 6. Isolated brain capillaries: an in vitro model of blood-brain barrier research; 7. Isolation and behavior of plasma membrane vesicles made from cerebral capillary endothelial cells; 8. Patch clamp technique with isolated brain microvessel membranes; 9. Tissue culture of brain endothelial cells - induction of blood-brain barrier properties by brain factors; 10. Brain microvessel endothelial cell culture systems; 11. Intracerebral microdialysis; 12. Blood-brain barrier permeability measured with histochemistry; 13. Measuring local cerebral capillary permeability-surface area products by quantitative autoradiography; 14. Measurement of blood-brain barrier permeability in humans using indicator diffusion; 15. Measurement of blood-brain barrier permeability in humans with positron emission tomography; 16. Magnetic resonance imaging of blood-brain barrier permeability; 17. Molecular biology of brain capillaries; Part II. Transport Biology: 18. Biology of the blood-brain glucose transporter; 19. Glucose transporters in mammalian brain development; 20. Blood-brain barrier amino acid transport; 21. P-glycoprotein, a guardian of the brain; 22. Blood-brain barrier ion transport; 23. Ion channels in endothelial cells; 24. Interactions of lipoproteins with the blood-brain barrier; 25. Fatty acid and lipid intermediate transport; 26. Blood-brain barrier transport of drugs; Part III. General Aspects of CNS Transport: 27. The blood-CSF barrier and the choroid plexus; 28. Arachnoid membrane, subarachnoid CSF and pia-glia; 29. Circumventricular organs of the brain; 30. Transport in the developing brain; Part IV. Signal Transduction/Biochemical Aspects: 31. Regulation of brain endothelial cell tight junction permeability; 32. Chemotherapy and chemosensitization; 33. Lipid composition of brain microvessels; 34. Brain microvessel antigens; 35. Molecular dissection of tight junctions: occludin and ZO-1; 36. Phosphatidylinositol pathways; 37. Nitric oxide and endothelin at the blood-brain barrier; 38. Role of intracellular calcium in regulation of brain endothelial permeability; 39. Cytokines and the blood-brain barrier; 40. Blood-brain barrier and monoamines, revisited; Part V. Pathophysiology in Disease States: 41. Cerebral amyloid angiopathy; 42. Brain microvasculature in multiple sclerosis; 43. Hemostasis and the blood-brain barrier; 44. Microvascular pathology in cerebrovascular ischemia; 45. HIV infection and the blood-brain barrier; 46. Hypertension; 47. The blood-brain barrier in brain tumours; 48. The pathophysiology of blood-brain barrier dysfunction due to traumatic brain injury; 49. Cerebral malaria and the brain microvasculature; 50. Molecular basis of tissue tropism of bacterial meningitis.


Best Sellers


Product Details
  • ISBN-13: 9780521034272
  • Publisher: Cambridge University Press
  • Publisher Imprint: Cambridge University Press
  • Height: 246 mm
  • No of Pages: 504
  • Series Title: English
  • Sub Title: Methodology, Biology and Pathology
  • Width: 188 mm
  • ISBN-10: 0521034272
  • Publisher Date: 14 Dec 2006
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Spine Width: 27 mm
  • Weight: 888 gr


Similar Products

How would you rate your experience shopping for books on Bookswagon?

Add Photo
Add Photo

Customer Reviews

REVIEWS           
Click Here To Be The First to Review this Product
Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology(English)
Cambridge University Press -
Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology(English)
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology(English)

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book
    Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    New Arrivals


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!
    ASK VIDYA