Learn the what, how, and why of pathophysiology! With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, McCance and Huether's Pathophysiology: The Biologic Basis for Disease in Adults and Children, 9th Edition helps you understand the most important and most complex pathophysiology concepts. This updated text includes more than 1,300 full-color illustrations and photographs to make it easier to identify normal anatomy and physiology, as well as alterations of function. It's the most comprehensive and authoritative pathophysiology text available! Unparalleled coverage of pathophysiology content makes this the most comprehensive and authoritative pathophysiology text on the market. Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment. Over 1,300 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes ? more than in any other pathophysiology text. Algorithms and flowcharts of diseases and disorders make it easy for you to follow the sequential progression of disease processes. Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content. Coverage of rare diseases and epigenetics further explores genetic disease traits. Obesity and Nutritional Disorders chapter thoroughly covers these growing global concerns. Chapter summary reviews provide concise synopses of the main points of each chapter. More than 30 3D animations on the companion Evolve website bring difficult concepts to life for a new perspective on disease processes. NEW! More than 50 new or revised illustrations visually reinforce pathophysiology concepts. NEW! Emerging Science boxes highlight the most current research and clinical developments.

Table of Contents:
PART ONE: Central Concepts of Pathophysiology: Cells and Tissues UNIT I: The Cell 1 Cellular Biology 2 Altered Cellular and Tissue Biology: Environmental Agents 3 The Cellular Environment: Fluids and Electrolytes, Acids and Bases UNIT II Genes, Gene-Environment Interaction, and Epigenetics 4 Genes and Genetic Diseases 5 Genes, Environment-Lifestyle, and Common Diseases 6 Epigenetics and Disease UNIT III Mechanisms of Self-Defense 7 Innate Immunity: Inflammation and Wound Healing 8 Adaptive Immunity 9 Alterations in Immunity 10 Infection 11 Stress and Disease UNIT IV Cellular Proliferation: Cancer 12 Cancer Biology 13 Cancer Epidemiology 14 Cancer in Children and Adolescents PART TWO: Pathophysiologic Alterations: Organs and Systems UNIT V The Neurologic System 15 Structure and Function of the Neurologic System 16 Pain, Temperature Regulation, Sleep, and Sensory Function 17 Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function 18 Alterations of the Brain, Spinal Cord, and Peripheral Nerves 19 Neurobiology of Schizophrenia, Mood Disorders, Anxiety Disorders, Posttraumatic Stress Disorder, and Obsessive-Compulsive Disorder 20 Alterations of Neurologic Function in Children UNIT VI The Endocrine System 21 Mechanisms of Hormonal Regulation 22 Alterations of Hormonal Regulation 23 Obesity, Starvation, and Anorexia of Aging UNIT VII The Reproductive Systems 24 Structure and Function of the Reproductive Systems 25 Alterations of the Female Reproductive System 26 Alterations of the Male Reproductive System 27 Sexually Transmitted Infections UNIT VIII The Hematologic System 28 Structure and Function of the Hematologic System 29 Alterations of Hematologic Function 30 Alterations of Hematologic Function in Children UNIT IX The Cardiovascular and Lymphatic Systems 31 Structure and Function of the Cardiovascular and Lymphatic Systems 32 Alterations of Cardiovascular Function 33 Alterations of Cardiovascular Function in Children UNIT X The Pulmonary System 34 Structure and Function of the Pulmonary System 35 Alterations of Pulmonary Function 36 Alterations of Pulmonary Function in Children UNIT XI The Renal and Urologic Systems 37 Structure and Function of the Renal and Urologic Systems 38 Alterations of Renal and Urinary Tract Function 39 Alterations of Renal and Urinary Tract Function in Children UNIT XII The Digestive System 40 Structure and Function of the Digestive System 41 Alterations of Digestive Function 42 Alterations of Digestive Function in Children UNIT XIII The Musculoskeletal System 43 Structure and Function of the Musculoskeletal System 44 Alterations of Musculoskeletal Function 45 Alterations of Musculoskeletal Function in Children UNIT XIV The Integumentary System 46 Structure, Function, and Disorders of the Integument 47 Alterations of the Integument in Children UNIT XV Multiple Interacting Systems 48 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults 49 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children Glossary