The Migraine Brain, edited by David Borsook, Arne May, Peter J. Goadsby, and Richard Hargreaves, makes a major contribution to the field, addressing the increasingly sophisticated neuroimaging techniques that have allowed researchers to begin to define functional and anatomical characteristics of migraine and other less-common types of headache. Of particular focus is how imaging is changing the way we understand migraine. This includes changes in function, structure and chemistry of the migraine brain. Included are sections that focus on particular aspects of migraine, for example the migraine aura: those symptoms that cause visual sensitivity (blinding white light), sensory difficulty (loud noises, painful touch, and hot/cold spells), slurred language, and motor dysfunction. Extensively illustrated throughout, The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches. A collation of the top thinkers in the field and the only book of its kind, The Migraine Brain is necessary reading for neurologists and neuroscientists.

Table of Contents:
I. Migraine: History Chapter 1: A History of Migraine, Mervyn Eadie II. Neurobiology of the Migraine Brain Chapter 2: Migraine - Some Theories and Controversies, Farooq Maniyar and Peter J. Goadsby Chapter 3: Neural System Changes in Migraine, Peter D. Drummond Chapter 4: Sensitization of Trigeminovascular Pathway: Implications to Migraine Pathophysiology, Rami Burstein and David Borsook Chapter 5: Brain Measures of the Interictal Migraine Brain State (IMBS), Nasim Maleki, Lino Becerra, and David Borsook Chapter 6: From Episodic to Chronic Migraine, Richard B. Lipton and Marcelo E. Bigal Chapter 7: Concomitant Symptoms in Migraine, Arne May & Anne Stankewitz III. Clinical Perspective Chapter 8: Clinical Neuroimaging of Migraine, Randolph W. Evans Chapter 9: Prophylaxis: What Measures?, Stephen Silberstein Chapter 10: Iron Accumulation in Migraine, Inge H. Palm-Meinders, Michel D. Ferrari, Mark C. Kruit Chapter 11 : Migraine and Brain Lesions, Inge H. Palm-Meinders, Michel D. Ferrari, Mark C. Kruit Chapter 12: Clinical Utility of Objective Measures, Franz Riederer, Andreas R. Gantenbein & Peter S. Sándor Chapter 13: Migraine Genes - Clinical and Preclinical Perspectives, Claudia M. Weller, Boukje de Vries, Gisela M Terwindt, Michel D. Ferrari, Joost Haan, and Arn M.J.M. van den Maagdenberg IV. Imaging Migraine Chapter 14: In Search of Future Treatments, Richard Hargreaves and David Dodick Chapter 15: Imaging migraine: A history, Jes Olesen and Peer Tfelt-Hansen Chapter 16: Focus on the Midbrain, Hans-Christoph Diener, Arne May Chapter 17: Diffusion Weighted Imaging in Migraine, Christos Sidiropoulos and Panayiotis D. Mitsias Chapter 18: DIFFUSION TENSOR IMAGING ABNORMALITIES IN MIGRAINE, Maria A. Rocca and Massimo Filippi Chapter 19: Morphometric changes and VBM, Arne May Chapter 20: SURFACE-BASED STRUCTURAL CHANGES IN MIGRAINE, Cristina Granziera Chapter 21: Changing receptors in Migraine state, Geneviève Demarquay and François Mauguière Chapter 22: 15O PET studies in migraine, Marie Denuelle, Pierre Payoux, Nelly Fabre and Gilles Geraud Chapter 23 : Imaging activation in the migraine state, Till Sprenger, Christian Seifert, Peter J. Goadsby Chapter 24: Metabolites and migraine, Caterina Tonon, Giulia Pierangeli, Sabina Cevoli, Pietro Cortelli, Raffaele Lodi Chapter 25: Visual aura, Nouchine Hadjikhani, Maurice B. Vincent Chapter 26: Functional Imaging of the Migraine Brain: New Insights into Brain Dysfunction, Eric A. Moulton Chapter 27: TMS and MEG studies in migraine, Sheena K Aurora, Sidra Saeed, and Susan M Bowyer Chapter 28: Magnetic Resonance Angiography and Migraine, M. Sohail Asghar and Messoud Ashina Chapter 29: Transcranial Magnetic Stimulation (TMS) / Repetitive Transcranial Magnetic Stimulation (rTMS), Magdalena Sarah Volz and Felipe Fregni Chapter 30: Measures of cortical excitability, Gianluca Coppola and Jean Schoenen Chapter 31: Drug Effects on Cortical Excitability, Susan M. Bowyer and Panayiotis D. Mitsias V. Conclusions Chapter 32: Defining the Migraine Phenotype, Todd J. Schwedt and David W. Dodick Chapter 33: The Future of Imaging in Migraine Diagnosis and Treatment, David Borsook and Lino Becerra Chapter 34: Can Imaging Effectively Transform Migraine Treatment?, David Borsook, Arne May, Peter Goadsby, Richard Hargreaves