A comprehensive and authoritative textbook, Neurological Therapeutics: Principles and Practice provides a reference that is both authoritative and accessible for daily use. The textbook explores the issues underlying treatment decisions not only for the most readily treated disorders but also for those conditions with few existing, definitive therapeutic options. With 600 figures, 37 in full color, tables, and a companion volume that is portable and easy-to-use, the final product is an important reference.

Table of Contents:
PRINCIPLES OF THERAPEUTICS Section Editor: John H. Noseworthy Basic Pharmaceutical Principles and the Blood Brain-Barrier Molecular Therapies for the Nervous System and Muscle Clinical Trial Methodology, FDA Terminology and Procedures Placebos Evidence-Based Medicine Ethical Issues in Neurological Treatment and Clinical Trials Domestic Violence in Neurological Practice PAIN: HEADACHE, SPINE AND LIMB PAIN Section Editor: John G. Emeads Principles of Pain Management Migraine Cluster Headache Tension-Type Headache Chronic Daily Headache Post-Traumatic Headaches Indomethacin-Responsive Headache Syndromes Giant Cell Arteritis Headache "Syndromes" in Children and Adolescents Diagnosis and Treatment of Common Orofacial Pain Conditions Radicular Limb Pain Back Pain Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy, Causalgia, Shoulder-Hand Syndrome) The Treatment of Central Pain Peripheral (Neuropathic) Pain Disorders Cancer Pain Fibromyalgia and Myofascial Pain Syndrome Pain Disorders SEIZURE DISORDERS Section Editor: Martha J. Morrell Classification and Epidemiology of Seizure Disorders: Therapeutic Implications and Importance The Pathophysiology of the Epilepsies Principles in Epilepsy: Diagnosis and Pharmacotherapy Antiseizure Drugs Surgery and Nonpharmacologic Therapies for Epilepsy Status Epilepticus The Treatment of Epilepsy in Children and Infants Seizures and Epilepsy in Women Epilepsy in the Elderly Imitators of Epilepsy Legal and Regulatory Issues for People With Epilepsy CEREBROVASCULAR DISEASE Section Editor: Jose Biller Principles of Atherosclerosis and Atherogenesis Stroke Prevention Anticoagulant Therapy and Antiplatelet Drugs Thrombolytic Therapy for Stroke Asymptomatic Carotid Artery Stenosis Transient Ischemic Attacks Management of Patients With Acute Ischemic Stroke Cardioembolic Stroke Cerebral Complications After Cardiac Surgery and Cardiac Arrest Hypoxic-Ischemic Encephalopathy Treatment of Intracerebral Hemorrhage Subarachnoid Hemorrhage Due to Cerebral Aneurysms Cerebral Aneurysms and Vascular Malformations Unruptured Intracranial Aneurysms Cervicocephalic Arterial Dissections Fibromuscular Dysplasia Venous Disorders Spinal Cord Vascular Syndromes Disorders of Coagulation Antiphospholipid Antibodies and Variants Systemic and Central Nervous System Vasculitides Hypertensive Encephalopathy Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Moyamoya Disease Stroke in Children Stroke in Pregnancy NEURO-ONCOLOGY Section Editor: J. Gregory Cairncross A Perspective on Neuro-Oncology Chemotherapy and Antineoplastic Agents Radiotherapy for CNS Neoplasms: Principles, Technologies and Indications Surgically Curable Brain Tumors of Adults Diagnosis and Treatment of Pituitary Tumors Diffuse Cerebral Gliomas in Adults Malignant Brain Tumors of Childhood Germ Cell Tumors and Primary Central Nervous System Lymphoma Brain Metastases Primary Tumors of the Spinal Cord, Root, Plexus, and Nerve Sheath Metastases to the Spine Meninges and Plexus Treatment of Paraneoplastic Neurological Syndromes Metabolic and Nutritional Complications Neurological Complications of Antineoplastic Treatment INFLAMMATORY AND INFECTIVE DISEASES Section Editors: Karen L. Roos and Hans-Peter Hartung Bacterial Meningitis Infectious Intracranial Mass Lesions Viral Meningitis and Encephalitis Tuberculosis and Other Mycobacterial Infections Neurosyphilis Lyme Disease Tetanus Rickettsial Infections Neurological Complications of HIV Infection Neurological Complications of HTLV-1 Infection Rabies Fungal Infections Protozoal Infections Helminthic Infections of the Central Nervous System Neurology of Arachnida (Spiders, Ticks, Scorpions) and Hymenoptera (Ants, Bees, Wasps) Envenomations Prion Diseases: Transmissible Spongiform Encephalopathies Perinatal Infections Infection in Solid Organ and Bone Marrow Transplant Recipients Behçet Disease: Diagnosis and Management Autoimmunity in the Nervous System Multiple Sclerosis and Related Conditions ICU NEUROLOGY Section Editor: Elco F.M. Wijdicks Therapy for Critically Ill Neurological Patients Airway Management and Mechanical Ventilation Management of Blood Pressure in Acute Neurological Illnesses Management of Increased Intracranial Pressure. Management of Sedation and Pain in the Intensive Care Unit Disturbances of Fluid and Electrolytes in Critically Ill Neurological Patients Anticoagulation and Thrombolysis in the Intensive Care Unit Management of Generalized Weakness in Medical and Surgical Intensive Care Units Organ Transplant Complications in the Intensive Care Unit Aspects of Metabolic Coma in the Intensive Care Unit Management of Head Trauma and Spinal Cord Injury in Adults Management of Nutrition NEUROLOGIC COMPLICATIONS OF SYSTEMIC ILLNESS (INCLUDING SLEEP DISORDERS, TOXIC, METABOLIC, NUTRITIONAL AND ENVIRONMENTAL DISORDERS) Section Editor: Martin A. Samuels Neurological Complications of Cardiac Procedures: Catheterization, Interventional Procedures and Surgery Cardiac Arrhythmias and Sudden Death Endocarditis (Infective and Non-Infective) Syncope Cardiomyopathy Cardiac Tumors Arterial Hypertension and Hypertensive Encephalopathy Hepatic Encephalopathy-Diagnosis and Management Acute Respiratory Failure in Neurological Disease Disorders of Excessive Sleepiness Parasomnias Disorders of Water and Sodium Balance Acid-Base Disturbances and the Central Nervous System Use of Therapeutic Plasma Exchange and Intravenous Immunoglobulin for the Treatment of Neurological Disease Megaloblastic Anemias-Vitamin B12, Folate Hemoglobinopathies and Thalassemias: Treatment of Stroke and Other Neurological Complications Therapy of the Neurological Complications of Lymphoma and Leukemia Neurological Disorders in Benign and Malignant Plasma Cell Dyscrasias Neurological Manifestations of Systemic Disease: Cryoglobulinemia Neurological Aspects of Transplantation Immunodeficiency Diseases Vasculitis Involving the Nervous System Neurological Manifestations of Rheumatoid Arthritis Cervical Spondylosis, Ankylosing Spondylitis, and Lumbar Disc Disease Neurological Complications of Progressive Systemic Sclerosis Treatment of Neurosarcoidosis Hypothalamus, Anterior and Posterior Pituitary and Adrenal (Including Disorders of Temperature Regulation) The Neurological Manifestations of Thyroid Disease Reproductive Endocrinology and Gender-Specific Issues in Neurology Disorders of Bone and Mineral Metabolism Lysosomal Storage Diseases Whipple Disease of the Nervous System Alcohol Stimulants, Sedatives, and Opiates Treatment of the Neurotoxic Effects of Organic Solvents Treatment of the Neurotoxic Effects of Gases: Carbon Monoxide, Hydrogen Sulfide, and the Nitrogen Oxides Pesticides Toxemia of Pregnancy Neuropathies and Neuromuscular Junction Disorders of Pregnancy Pregnancy and Multiple Sclerosis: Therapeutic Aspects Movement Disorders During Pregnancy Mitochondrial Disease PEDIATRIC AND ADOLESCENT NEUROLOGY Section Editor: Russell D. Snyder The Neurological Examination of the Infant and Child Perinatal Neurology Developmental Problems of the Brain, Skull and Spine Mental Retardation and Cerebral Palsy Disorders of Learning and Behavior in Children Chromosomal Disorders, Inborn Errors of Metabolism and Degenerative Diseases Neurocutaneous Disorders Pediatric Brain and Spinal Cord Injury CRANIAL NERVE DISORDERS (INCLUDING NEURO-OTOLOGY AND NEURO-OPHTHALMOLOGY) Section Editor: James A. Sharpe Disturbances of Smell and Taste Optic Neuropathies Papilledema and Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) Chiasm and Retrochiasmal Disorders Disturbances of the Pupil Ocular Motor Nerve Palsies Nystagmus and Saccadic Oscillations Gaze Disorders Ocular Myasthenia Gravis Cavernous Sinus Disorders Trigeminal Neuropathy and Neuralgia. Disorders of the Facial Nerve Vertigo, Vestibular Nerve, and Central Vestibular Disorders Disorders of the Inner Ear Tinnitus and Deafness Disorders of the Glossopharyngeal, Vagus, Accessory, and Hypoglossal Nerves. Multiple Cranial Nerve Palsies Functional Diseases Affecting the Cranial Nerves PERIPHERAL NERVE DISORDERS (INCLUDING ANTERIOR HORN CELL, AND AUTONOMIC NERVOUS SYSTEM) Section Editor: Peter J. Dyck Mechanical Nerve Injuries Varicella Zoster Virus, Herpes Simplex Virus, Bell's Palsy Peripheral Nervous System Lyme Disease Diphtheritic Neuropathy Peripheral Neuropathy and HIV The Neuropathies of Leprosy Peripheral Neuropathies in Chagas Disease Late Effects of Polio Diabetic Polyneuropathy Diabetic Radiculoplexus Neuropathies Peripheral Neuropathy Associated With Hypothyroidism and Acromegaly Multiple Endocrine Neoplasia, Type 2B Neuropathies in Liver Disease and Chronic Renal Failure Peripheral Neuropathy Associated with Alcoholism, Malnutrition, and Vitamin Deficiencies Acute Inflammatory Demyelinating Polyradiculoneuropathy, Acute Motor Axonal Neuropathy and Acute Motor and Sensory Axonal Neuropathy Chronic Inflammatory Demyelinating Polyradiculoneuropathy Miller Fisher Syndrome Brachial Plexus Neuropathy Nondiabetic Lumbosacral Radiculoplexus Neuropathy Treatment of Non-malignant Sensory Ganglionopathies Vasculitis of the Peripheral Nervous System The Treatment of Multi-focal Motor Neuropathy With Conduction Block (MMN-CB) Sarcoidosis and Peripheral Neuropathy Neuropathy Associated With the Monoclonal Gamopathies. Amyloidosis Peripheral Neuropathy in the Lymphomas and Leukemias Paraneoplastic Neuropathy Syndromes: Principles and Treatment Inherited Neuropathies With Known Metabolic Derangement Porphyria. Hereditary Sensory and Autonomic Neuropathies Hereditary Motor Neuropathies Hereditary Neuropathy With Liability to Pressure Palsy Hereditary Spinocerebellar Degeneration Motor Neuron Diseases. Neurotoxic Metals Critical Illness Polyneuropathy Paresthesias and Pain Treatment of Sexual Dysfunction and Cystopathy in Peripheral Nerve Disorders Gastrointestinal Dysmotility and Sphincter Dysfunction Neurogenic Orthostatic Hypotension Orthostatic Intolerance Treatment of Central Autonomic Disorders MUSCLE DISEASES Section Editor: Andrew E. Engel Principles of Muscle Disorders Congenital Myopathies Muscular Dystrophies Inflammatory Myopathies Metabolic Myopathies Disorders of Voltage-Gated Ion Channels Myasthenia Gravis and Myasthenic Syndromes Malignant Hyperthermia Stiff-Man Syndrome Cramps and Myalgias DEGENERATIVE DISEASES (MOVEMENT DISORDERS) Section Editors: Stanley Fahn and Blair Ford Principles of Movement Disorders Medical Treatment of Parkinson's Disease and Its Complications Parkinsonism Plus Disorders Surgical Treatment of Parkinson's Disease The Diagnosis and Treatment of Normal Pressure Hydrocephalus Syringomyelia. Focal Dystonias: Blepharospasm, Cervical Dystonia, Spasmodic Dysphonia, Writer's Cramp Generalized Torsion Dystonia. Dopa-Responsive Dystonia (DRD) Huntington Disease Neuroacanthocytosis Sydenham Chorea Ballism and Chorea Essential Tremor Treatment of Orthostatic Tremor Myoclonus Dentatorubral-pallidoluysian Atrophy (DRPLA) Tardive Dyskinesia and Related Syndromes Tourette Syndrome and Tic Disorders Paroxysmal Dyskinesias Painful Legs and Moving Toes The Restless Legs Syndrome and Periodic Movements of Sleep Treatment of Hemifacial Spasm Wilson's Disease Psychogenic Movement Disorders Hereditary Ataxias and Other Cerebellar Degenerations Therapy of Human Prion Diseases Hereditary Spastic Paraplegia NEUROBEHAVIOR AND NEUROPSYCHIATRY Section Editor: Kenneth M. Hellman Treatment of Disorders of Cognition: An Introduction Aphasia Treatment of Alexia and Agraphia Treatment of Developmental Language Disorders Treatment of Neglect Management of Attention-Deficit/Hyperactivity Disorder and Dyslexia (Specific Reading Disability) Limb Apraxia Intentional Disorders Evaluation and Management of Amnesic Disorders Executive Disorders Alzheimer Disease and Mild Cognitive Impairment Diagnosis and Management of the Non-Alzheimer Dementias Behavioral and Emotional Complications of Neurological Disorders Treatment of Emotional Communication Disorders