Neurology: A Queen Square Textbook, second edition, is a fully revised and updated companion that demonstrates the rapid pace of advancement within clinical neurology and applied neuroscience A comprehensive and practical overview of current developments within clinical neurology, synthesising clinical neurology with translational research Expertly edited and written by neurologists, neuroscientists and neurosurgeons working at Queen Square, advised by an distinguished International Editor team to present a global perspective Introductory chapters summarise the basic sciences underpinning the practice of clinical neurology, including genetics, channelopathies, immunology, neurophysiology and neuropathology All chapters fully revised and updated to reflect the increasing role of neurologists in acute care Includes new contributions concerning major developments in the care of; stroke, epilepsy, dementia, Parkinson's disease, multiple sclerosis, neuromuscular disease, headache, infections, spinal disease, cranial nerve disease, neuropsychiatry, neurogenetics, neuro-oncology, uroneurology, neuro-otology, neuro-ophthalmology, pain medicine, sleep medicine, metabolic disease, drugs and toxins, autonomic disease, systemic disease, and neurorehabilitationfor dementia, epilepsy, headaches, neuro-genetics and many more

Table of Contents:
Editorial Team vii Principal Editors vii International Editors vii Specialist Advisory Editors vii Authors vii Beginnings xi Foreword to the First Edition xiii Foreword to the Second Edition xv Preface xvii Acknowledgements xix 1 Neurology Worldwide: The Epidemiology and Burden of Neurological Disease 1 Simon Shorvon 2 Nervous System Structure and Function 11 Charles Clarke and Roger Lemon 3 Mechanisms of Neurological Disease: Genetics, Autoimmunity and Ion Channels 69 Dimitri Kullmann, Henry Houlden and Michael Lunn 4 The Language of Neurology: Symptoms, Signs and Basic Investigations 97 Charles Clarke, Matthew Adams, Robin Howard, Martin Rossor, Simon Shorvon and Jason Warren 5 Stroke and Cerebrovascular Diseases 133 Nicholas Losseff, Matthew Adams, Martin M. Brown, Joan Grieve and Robert Simister 6 Movement Disorders 187 Kailash Bhatia, Carla Cordivari, Mark Edwards, Thomas Foltynie, Marwan Hariz, Prasad Korlipara, Patricia Limousin, Niall Quinn, Sarah Tabrizi and Thomas Warner 7 Epilepsy and Related Disorders 221 Simon Shorvon, Beate Diehl, John Duncan, Matthias Koepp, Fergus Rugg‐Gunn, Josemir Sander, Matthew Walker and Tim Wehner 8 Dementia and Cognitive Impairment 289 Martin Rossor, John Collinge, Nick Fox, Simon Mead, Catherine Mummery, Jonathan Rohrer, Jonathan Schott and Jason Warren 9 Infection in the Nervous System 337 Robin Howard, Carmel Curtis and Hadi Manji 10 Nerve and Muscle Disease 391 Michael Lunn, Michael Hanna, Robin Howard, Matthew Parton, Shamima Rahman, Mary Reilly, Katie Sidle and Christopher Turner 11 Multiple Sclerosis and Demyelinating Diseases 475 Siobhan Leary, Gavin Giovannoni, Robin Howard, David Miller and Alan Thompson 12 Headache 513 Manjit Matharu, Paul Shanahan and Tim Young 13 Cranial Nerve Disorders 531 Jeremy Chataway, Charles Clarke, Robin Howard and Paul Jarman 14 Neuro‐Ophthalmology 553 James Acheson, Fion Bremner, Elizabeth Graham, Robin Howard, Alexander Leff, Gordon Plant, Simon Shorvon and Ahmed Toosy 15 Neuro‐Otology: Problems of Dizziness, Balance and Hearing 605 Rosalyn Davies, Linda M. Luxon, Doris‐Eva Bamiou and Adolfo Bronstein 16 Spinal Column and Spinal Cord Disorders 647 Simon Farmer and David Choi 17 Cerebellar Ataxias and Related Conditions 685 Nicholas W. Wood 18 Restorative Neurology, Rehabilitation and Brain Injury 699 Richard Greenwood, Diana Caine, Ulrike Hammerbeck, Alexander Leff, Diane Playford, Valerie Stevenson and Nick Ward 19 Toxic, Metabolic and Physical Insults to the Nervous System and Inherited Disorders of Metabolism 729 Robin Howard, Jeremy Chataway, Mark Edwards, Simon Heales, Robin Lachmann, Alexander Leff and Elaine Murphy 20 Disorders of Consciousness, Intensive Care Neurology and Sleep 797 Robin Howard, Sofia Eriksson, Nicholas Hirsch, Neil Kitchen, Dimitri Kullmann, Christopher Taylor and Matthew Walker 21 Neuro‐Oncology 849 Jeremy Rees, Robert Bradford, Sebastian Brandner, Naomi Fersht, Rolf Jäger and Elena Wilson 22 Neuropsychiatry 905 Eileen Joyce 23 Pain 919 Paul Nandi 24 Autonomic Aspects of Neurology 945 Christopher Mathias, Gordon Ingle and Valeria Iodice 25 Uroneurology 967 Jalesh Panicker 26 Systemic Conditions and Neurology 985 David Werring, Robin Howard and Simon Shorvon Index 1029