Neurologic and neuropsychiatric disorders are of great importance to societies and they also raise special considerations in epidemiological research methodology. Not only do neurologic and neuropsychiatric disorders form a major group of disorders associated with ageing populations, but those disorders that occur in earlier life can be associated with severe individual, family, and societal distress and burden. The inter-relationship of syndromes and disorders is a topic of major interest and growing biological insights across psychiatry and neurology. This includes not only overlaps in neurodegenerative syndromes but also those related to other systems such as metabolic, inflammatory, immune and vascular disorders. Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology is designed to focus on the overlaps and inter-relationships between neuro-epidemiological disorders, as well as on ways to harmonise large cohort studies to maximise opportunities for determining causes related to rarer disorders. Divided into three main parts, the book covers 1) the principles of neurologic and neuropsychiatric epidemiology; 2) specific neuropsychiatric disorders and their inter-relationships and 3) the implications of neuro-epidemiologic research for patient populations and current medical practice. This comprehensive work serves as an invaluable reference to current neuro-epidemiological methods for neurologists, psychiatrists, and senior trainees in those disciplines, as well as public health practitioners and students with an interest in neurology and neuropsychiatry.

Table of Contents:
1: German E. Berrios and Ivana S. Marková: A historical perspective on neurological and neuropsychiatric definitions 2: V.R. Varma, Y. F. Chuang, and M. Thambisetty: Neuroimaging and fluid biomarkers of Alzheimer s disease: implications for definition, diagnosis and treatment 3: Yoav Ben-Shlomo: Life course, exposure, and ageing populations 4: Kenneth M. Langa, Eileen Crimmins, and Mark D. Hayward: Examining trends in dementia incidence and prevalence using an age-period-cohort framework 5: Derrick A. Bennett: Overview of common designs, measures of effect, and biases in neuro-epidemiological studies 6: Maëlenn Guerchet, Rosie Mayston, and A. Matthew Prina: Conducting research in low and middle income settings. 7: Edo Richard: Trial designs including observational to interventional 8: Chengxuan Qiu, Davide Liborio Vetrano, and Laura Fratiglioni: Cardiometabolic morbidities and dementia 9: Ratnavalli Ellajosyula: Early onset Alzheimer s disease 10: Juliana R. Dutra: Huntington s Disease 11: Valentina Gallo, Tanya P. Garcia, and Karen Marder: Idiopathic Parkinson s disease and classification of Parkinsonisms 12: Rodolfo Savica and Pierpaolo Turcano: Dementia and Parkinson s disease 13: Giancarlo Logroscino and Adriano Chiò: FTD and ALS 14: James B. Rowe and Ian T.S. Coyle-Gilchrist: Rare Neurodegenerative Parkinsonism (PSP, MSA, CBD) 15: Keir X. X. Yong, S. J. Crutch, and J. M. Schott: Posterior Cortical Atrophy 16: Elan D. Louis: Epidemiology of essential tremor 17: Amy R. Borenstein: Detecting dementia early in populations 18: María M. Corrada and Claudia H. Kawas: The oldest-old and dementia at the end of life 19: Rita V. Krishnamurthy and Valery L. Feigin: Global stroke burden and prevention strategies- findings from GBD 2015 20: Bo Norrving, MD, PhD: Stroke and TIA 21: Fergus Doubal, Anna Poggesi, Leonardo Pantoni, and Joanna Wardlaw: Small vessel disease 22: Julio R. Vieira and Richard B. Lipton: Migraine: Descriptive epidemiology and related neurobiology 23: Stina Saunders, Graciela Muniz-Terrera , Tom C. Russ, Craig W. Ritchie, and Karen Ritchie: The clinical spectrum of neurodegenerative disease: moving beyond Mild Cognitive Impairment 24: Sergio Starkstein, Bradleigh Hayhow, and Pierre Wibawa: The epidemiology of apathy in neurological disorders 25: Rianne van der Linde and Tom Dening: Behavioural and Psychological Symptoms of Dementia 26: Daniel Davis, Sarah Richardson, and Esteban Sepulveda: Delirium 27: Mirjam I. Geerlings: Methods and approaches to examining the interface of late-life depression and dementia 28: Assen Jablensky, H. E. Jongsma HE, James B. Kirkbride, and Peter B. Jones: Epidemiology of schizophrenia and related disorders 29: Elisabeth Gulowsen Celius: Multiple sclerosis: Descriptive epidemiology and related neurobiology 30: Anne Taraldsen Heldal and Nils Erik Gilhus: Myasthenia gravis 31: Ettore Beghi, Giorgia Giussani, and Torbjorn Tomson: Epilepsy 32: Ettore Beghi, Giorgia Giussani, and Marco Poloni: Neuropathies: Descriptive epidemiology and related neurobiology 33: Paul J. Foster, Anthony Khawaja, Lisanne J. Balk, Zaynah Muthy, and Axel Petzold: Sensory loss Vision 34: Adele M. Goman and Frank R. Lin: Sensory loss - Hearing 35: Patrick J. M. Urwin and Anna M. Molesworth: The Neuroepidemiology of Human Prion Disease 36: Charles R. Newton: Epidemiology of bacterial and parasitic infections of the central nervous system 37: Inès Yoro-Zohoun, Jaime Luna, Salmane Amidou, and Pierre-Marie Preux: Infection: other than bacterial, including HIV 38: Alice Theadom and Kelly M. Jones: Traumatic brain and spinal cord injury 39: Joachim Schüz and Maria Feychting: Electromagnetic fields 40: Susan Peters, Anne E. Visser, Marc Weisskopf, Marianthi-Anna Kioumourtzoglou, and Roel Vermeulen: Metals and neurodegeneration 41: Thomas Truelsen, Catherine Johnson, Mohsen Naghavi, Theo Vos, Valery L. Feigin, and Gregory Roth: Estimating the global burden of stroke: methods and challenges 42: Carol Brayne: What is the role of trials and other well designed studies in the understanding of neurological and neuropsychiatric conditions 43: Ann I. Scher, David W. Niebuhr, and Darrell Singer: Research and methodologic opportunities and challenges conducting research among U.S military personnel 44: Adesola Ogunniyi: Global evidence generation 45: Giancarlo Logroscino, Carol Brayne, and Rosanna Tortelli: The role of prevention in common neurological disorders