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Polyphosphazenes for Biomedical Applications

Polyphosphazenes for Biomedical Applications

          
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About the Book

This book serves as both an introduction and a practical guide on the synthesis and use of polyphosphazenes, a new and very versatile polymer family which has recently demonstrated bioactivity, biocompatibility, and biodegradability. These polymers find uses as potent vaccine adjuvants and microencapsulating agents; biodegradable materials and scaffolds for tissue engineering; biocompatible coatings and carriers for gene delivery, for example. A broad spectrum of application specialists working in chemistry, life scientists, and chemical engineering will appreciate this single-source reference.

Table of Contents:
CONTRIBUTORS. PREFACE. I INTRODUCTION. 1 Polymers for Biology and Medicine - Current Status and Future Prospects ( Alexander K. Andrianov and Robert Langer ). 2 Expanding Options in Polyphosphazene Biomedical Research ( Harry R. Allcock ). II VACCINE DELIVERY AND IMMUNOMODULATION. 3 Polyphosphazenes as Vaccine Delivery Systems ( Alexander K. Andrianov ). 4 The Potential of Polyphosphazenes in Modulating Vaccine-Induced Immune Responses I: Investigations In Mice ( George Mutwiri, Ponn Benjamin, Alexander K. Andrianov, and Lorne Babiuk ). 5 The Potential of Polyphosphazenes in Modulating Vaccine-Induced Immune Responses II: Investigations In Large Animals ( George Mutwiri and Lorne Babiuk ). 6 Polyphosphazenes as Adjuvants for Inactivated and Subunit Rotavirus Vaccines in Adult and Infant Mice ( Kari Johansen, Jorma Hinkula, Claudia Istrate, Elin Johansson, Didier Poncet, and Lennart Svensson ). 7 Polyphosphazene Immunoadjuvants for Intradermal Vaccine Delivery ( Alexander K. Andrianov, Daniel P. DeCollibus, Helice A. Gillis, Henry H. Kha, Alexander Marin ). III BIOMATERIALS. 8 Biodegradable Polyphosphazene Scaffolds for Tissue Engineering ( Syam P. Nukavarapu, Sangamesh G. Kumbar, Harry R. Allcock and Cato T. Laurencin ). 9 Biodegradable Polyphosphazene Blends for Biomedical Applications ( Meng Deng, Lakshmi S. Nair, Nicholas R. Krogman, Harry R. Allcock, Cato T. Laurencin ). 10 Polyphosphazenes from Condensation Polymerization ( Patty Wisian-Neilson ). 11 Electrospun Polyphosphazene Nanofibers For In Vitro Osteoblast Culture ( Maria Teresa Conconi, Paolo Carampin, Silvano Lora, Claudio Grandi, Pier Paolo Parnigotto ). 12 Phosphazenes and Surfaces ( Mario Gleria, Roberto Milani, Roberta Bertani, Angelo Boscolo Boscoletto, and Roger De Jaeger ). IV DRUG DELIVERY SYSTEMS. 13 Amphiphilic Ionizable Polyphosphazenes for the Preparation of pH-Responsive Liposomes ( David Ghattas and Jean-Christophe Leroux ). 14 Poly- and Cyclophosphazenes as Drug Carriers for Anticancer Therapy ( Youn Soo Sohn and Yong Joo Jun ). 15 Amphiphilic Polyphosphazenes as Drug Carriers ( Liyan Qiu and Cheng Zheng ). 16 Synthesis and Characterization of Organometallic Derivatives of Polyphosphazenes and their Applications in Nanoscience ( Carlos Diaz and M. L. Valenzuela ). 17 Transport Properties of Polyphosphazenes ( Joel R. Fried ). V BIODETECTION. 18 Potentiometric Monitoring Antibody-Antigen Interactions by and Stabilization of Polyanilineand Electrodes with p -Sulfonated Poly(bisphenoxyphosphazene) ( Byeongyeol Kim, Alexander K. Andrianov, Alok Prabhu, Vladimir Sergeyev, and Kalle Levon ). VI WELL-DEFINED POLYPHOSPHAZENES: SYNTHETIC ASPECTS AND NOVEL MOLECULAR ARCHITECTURES. 19 Synthesis and chemical regularity in phosphazene copolymers ( Gabino A. Carriedo ). 20 Supramolecular Structures of Cyclophosphazenes( Alexander Steiner APPENDIX A. INDEX.


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Product Details
  • ISBN-13: 9780470478882
  • Publisher: John Wiley and Sons Ltd
  • Publisher Imprint: Wiley-Blackwell
  • Height: 250 mm
  • No of Pages: 480
  • Spine Width: 15 mm
  • Width: 150 mm
  • ISBN-10: 0470478888
  • Publisher Date: 10 Nov 2008
  • Binding: Other digital
  • Language: English
  • Returnable: Y
  • Weight: 666 gr


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