This is the seventh monograph in the series Progress and Controversies in Oncologic Urology (PACIOU). Containing contributions from experts from around the globe, this book provides the most up-to-date information available on the mechanisms and treatment of prostate cancer and male sexual dysfunction. Highlighting the relationship between research results and the clinical practice, the discussions include the diagnosis and therapy of benign prostate cancer, diagnosis and outcomes in locally confined prostate cancer, epidemiology, risk factors, renal cancer, and the results of phase I and phase II trials of new drug treatments.

Table of Contents:
SEXUAL FUNCTION: MECHANISMS AND TREATMENT
Sexual Health of the Aging Male, E.J.H. Meuleman
Determinants of Sexual Function in the Aging Male, J.L.H.R. Bosch
The Impact of Radical Prostatectomy and Primary Radiotherapy for Localized Prostate Cancer on Quality of Life, M.L. Essink-Bot, I.J. Korfage, H.J. de Koning
Sexual Function Before and After Radical Retropubic Prostatectomy: A Prospective Analysis, G.R. Dohle, Y.D. Dubbelman, S.F.M. Broersen, M. Wildhagen and F.H. Schröder
Effects of Endocrine Treatment - Can Libido and Sexual Function be Preserved? P. Iversen
Oral Therapy, H. Porst
Intracavernosal Injection Therapy for Erectile Dysfunction: An Update, F. Montorsi
Mechanisms and Prevention of Erectile Dysfunction after Radiotherapy for Prostate Cancer, L. Incrocci

BENIGN PROSTATE HYPERPLASIA: PROGRESS AND CONTROVERSY IN DIAGNOSIS AND THERAPY
Evaluation and Management of Lower Urinary Tract Symptoms Related to Benign Prostate Disease: The Contribution of the International Continence Society (ICS)- 'Benign Prostatic Hyperplasia' Study, J.L. Donovan
Distinguishing Nocturnal Polyuria from Benign Prostatic Hyperplasia-Related Nocturnia: Simple Algorithms for General and Urological Practice, M.H. Blanker and J. Prins
Practical Application of Non-Invasive Tests to Grade Outflow Obstruction and Bladder Contractility: The End of Classical Urodynamics? J.J.M. Pel, J.W.M.C. Huang Foen Chung, and R. van Mastrigt
Screening for Prostate Cancer within the Benign Prostatic Hypertrophy Population: Current Evidence and Future Directions, M.R. Cooperberg and P.R. Carroll
Androgen Supplementation in Older Men: What is the Impact on PSA, Prostate Growth, and Lower Urinary Tract Symptoms? L.J.G. Gooren and M. Bunck

BASIC RESEARCH ON PROSTATE CANCER
Diagnosis, Classification, and Therapy Development for Human Prostate Cancer Using Biochip Technologies and Post-Genomic Era Molecular Medicine, O.P. Kallioniemi, M. Wolf, L. Bubendorf and S. Mousses
Candidate Genetic Markers and Therapeutic Targets in Hereditary and Sporadic Prostate Cancer, P. Berthon
Basic Research on Prostate Cancer : Signal Transduction, Z. Culig
Stem Cells and Differentiation in Human Prostate Cancer, J.R. Masters, T.N. Alam, C.L. Foley, I. Laczkó and D.L. Hudson
Role of the Stromal Micro Environment in Carcinogenesis of the Prostate, G.R. Cunha, S.W. Hayward, Y.Z. Wang and W.A. Ricke
Prostate Cancer Xenograft Models, J.C. Romijn
Hormonal Regulation of Prostate Cancer, C.A. Berrvoets, A. Umar and A.O. Brinkmann
Profiling Protein Interactions in Angiogenesis, R. Pasqualini and W. Arap

TRANSLATIONAL RESEARCH INPROSTATE CANCER: WHAT IS CLOSE TO CLINICAL PRACTICE
The Immunotherapy of Prostate Cancer, G. Dalgleish
Prognostic Tissue Factors for Prostate Cancer: Recent Developments and Pitfalls, M.A. Noordzij
Diagnostic Markers for Prostate Cancer Detected in Serum, Plasma or Blood; Prostate-Specific Antigen-Forms and Human Kallikrein 2 (hK2) for Early Detection and Staging, H. Huland, A. Haese and H. Lilja
Expected Impact of New Technologies on Prostate Cancer Research, G. Jenster

DIAGNOSIS AND OUTCOME IN LOCALLY CONFINED PROSTATE CANCER
Predictive Algorithms and their Clinical Relevance, M. Graefen and H. Huland
Defining the Proper 'Window of Opportunity' in the Early Detection of Prostate Cancer, A.N. Vis
Screening for Prostate Cancer: Views from the UK and the Rest of the World, F.C. Hamdy
Outcome after Radical Prostatectomy - How Predictive are Biopsy versus Radical Prostatectomy Specimens? L. Boccon-Gibod, L. Nicolas, O. Dumonceau, V. Ravery, M. Toublanc, Li Boccon-Gibod

PROSTATE CANCER, EPIDEMIOLOGY, RISK FACTORS, AND OUTCOMES PER TREATMENT
A Randomized Trial Comparing Radical Prostatectomy with Watchful Waiting in Early Prostate Cancer, H. Haggman,
Prostate Cancer Mortality and Screening, S. Oliver
Expectant Management with Selective Delayed Intervention for Favorable Risk Prostate Cancer, L. Klotz
Is Cure of Prostate Cancer Possible in those in Whom it is Necessary, P.C. Walsh

RENAL CANCER
Modern Molecular Classification of Renal Cell Carcinoma: Relevance for Urologists? F. Algaba
Prognostic Factors for Renal Cell Carcinoma, Z. Kirkali, E. Tuzel and M. Ugur Mungan
High-Tech Diagnostic Procedures in RCC: Promise and Practice, G.P. Krestin and F. Cademartiri
Technical and Surgical Progress in Organ-Sparing Approaches for RCC,J. Hoang-Boam and P. Alken
Surgery for Renal Cell Carcinoma: The Case for Open Surgery, D. Jacqmin
Laparoscopic Partial Nephrectomy: Pro, J. Rassweiler and S.K.H. Yip
Laparoscopic Radical and Nephrectomy - Pro, D. Teber, V. Moraga, S. Yip, Y. Dekel, T. Frede, O. Seeman and J. Rassweiler
Clinical Research Avenues in Metastactic Renal Cell Carcinoma, G.H.J. Mickisch

PROSTATE CANCER, LOCALLY ADVANCED AND NODE POSITIVE
Diet and Prostate Cancer, K. Griffith, L.J. Denis and A. Turkes
Determinants of Prostate Cancer-Specific Survival Following Radiation Therapy for Patients with Clinically Localized Prostate Cancer, A.V. D'Amico
Use of Adjuvant Hormonal Therapy with Radical Prostatectomy in N+ Disease: Rationale and Contribution to Outcome, R.P Myers, E.J. Bergstralh, J.M. Slezak, G.M. Farrow, M.M. Lieber, M.L. Blute and H. Zincke

ADVANCED PROSTATE CANCER
Side Effects of Endocrine Treatment: Role of Duration of Treatment, D. Kirk
Chemotherapy for the Treatment of Hormone-Refractory Prostate Cancer: Evaluating New Targets Based on Apoptotic Pathways, D.P. Petrylak
The Role of Biphosphonates in Prostatic Cancer, D.S. Ernst
Direct from the Pipeline: Results of Phase I and II Studies of New Drugs, C. Sternberg
Chemotherapy in the Management of Prostate Cancer, C. Logothetis and R.E. Millikan