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Protine Kinase: Extracellular Signal-Regulated Kinases, Akt1, Lkb1, Protine Kinase A, Serum and Glucocorticoid-Regulated Kinase(French)

Protine Kinase: Extracellular Signal-Regulated Kinases, Akt1, Lkb1, Protine Kinase A, Serum and Glucocorticoid-Regulated Kinase(French)

          
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About the Book

Les achats comprennent une adhsion l'essai gratuite au club de livres de l'diteur, dans lequel vous pouvez choisir parmi plus d'un million d'ouvrages, sans frais. Le livre consiste d'articles Wikipedia sur: Extracellular Signal-Regulated Kinases, Akt1, Lkb1, Protine Kinase A, Serum and Glucocorticoid-Regulated Kinase. Non illustr. Mises jour gratuites en ligne. Extrait: Les protines ERK1/2 sont des enzymes, des kinases, qui ajoutent des groupements phosphate d'autres protines afin de les activer. ERK1/2 font partie de la famille des MAP kinases qui sont des protines jouant un rle dans la division, la croissance et la prolifration cellulaires. FIGURE 1: Structure 3D de ERK-2 chez l'humain (il n'existe pas encore ce jour une structure 3D comme celle-ci pour ERK-1 chez l'humainLes protines ERK-1 et ERK-2 signifiant Extracellular signal-regulated kinases sont des protines codes par les gnes 16p11.2 pour ERK-1 et 22p11.2 pour ERK-2. Ce sont deux isoformes respectivement de poids molculaires de 43 kDa (379 acides amins) et 41 kDa (360 acides amins) chez l'humain. Quand ces protines deviennent phosphoryles, elles acquirent un poids molculaire de 44 kDa et 42 kDa respectivement pour ERK-1 et pour ERK-2. Bien que ERK-1 et ERK-2 possdent plusieurs autres noms (voir tableau 1), les chercheurs les nomment couramment ERK1/2. Ces deux enzymes ont un degr d'homologie de 83%, car on remarque une similitude dans la squence et la composition de leurs acides amins. ERK1/2 sont des kinases qui sont actives par l'ajout obligatoire de deux groupements phosphate une thronine (T) et une tyrosine (Y): T202 et Y204 pour ERK-1 et T184 et Y186 pour ERK-2. Ces protines kinases ajoutent elles aussi un ou des groupement(s) phosphate des endroits spcifiques, particulirement sur des rsidus tyrosine, thronine ou srine pour activer leur tour d'autres protines. ERK1/2 font partie de la famille des MAP kinases, ...http: //booksllc.net/?l=fr


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Product Details
  • ISBN-13: 9781159907983
  • Publisher: Books LLC
  • Publisher Imprint: Books LLC
  • Height: 152 mm
  • No of Pages: 34
  • Series Title: French
  • Sub Title: Extracellular Signal-Regulated Kinases, Akt1, Lkb1, Protine Kinase A, Serum and Glucocorticoid-Regulated Kinase
  • Width: 229 mm
  • ISBN-10: 1159907986
  • Publisher Date: 06 Aug 2010
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Spine Width: 2 mm
  • Weight: 64 gr


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