Reports on new radiosurgery technologies, the use of novel imaging techniques for dose planning and results analyses, outcomes for patients with benign and malignant brain tumors, vascular malformation radiosurgery, and radiobiology and physics studies are the main themes in this third volume of the peer-reviewed high-quality book series ‘Radiosurgery’. It provides reports from the 1999 meeting of the International Stereotactic Radiosurgery Society (ISRS) in Sydney, Australia. As the medical field of radiosurgery grows scientifically, a record number of scientific submissions for publication were received. A selection of the important topics discussed in the ISRS meeting are presented in this volume. This publication is of special interest to neurologists, neurosurgeons and radiation oncologists who need up-to-date and precise information to keep up with the important developments in the field and their impact on the management of brain disease.

Table of Contents:
Introduction - gamma knife surgery - evolution and long-term results, C. Lindquist. Part 1 Advances in technology: quantitative verification of dose distributions for linac radiosurgery and fractionated stereotactic radiotherapy, S.L. Meeks et al; image-guided robotic radiosurgery - clinical and radiographic results with the cyberknife, S.D. Chang et al; clinical experience with the cyberknife at Newport Radiosurgery Centre, S.G. Chenery et al; a phase-space model for simulating arbitrary intensity distribution for shaped radiosurgery beams using the Monte Carlo method, I. Chetty et al; conformal radiosurgery using a dedicated linac and micro multileaf collimator, T.D. Solberg et al; micro intensity-modulated radiotherapy for intracranial tumors - a case study, M. Bues et al; a technique for verification of three-dimensional radiosurgical dose distributions, J.L. Robar and B.G. Clark; clinical dosimetry considerations for a doubled-focused miniature multileaf collimator, S.L. Meeks et al; conformal static field stereotactic radiotherapy for larger intracranial lesions, F.L. Hacker et al; three methods of beam shaping in Xknife-3 stereotactic radiotherapy, Y.C. Ahn et al. Part 2 Imaging and radiosurgery: assessment of the accuracy of volume determination using stereotactic magnetic resonance imaging, J. Novotny, Jr. et al; registration of SPECT onto CT images using a BrainLab stereotactic radiosurgery planning system, W.S. Jaafar et al; functional magnetic resonance imaging for stereotactic radiosurgery, M. Schulder et al. Part 3 Radiobiology: an in vivo CT study of blood-brain barrier permeability and vascular volume in a brain tumor model - potential applications to stereotactic radiosurgery, L.L. Stevens et al; radioprotection of normal brain tissue by the Lazzaroid U74389G is not improved by dose escalation, J.M. Buatti et al. Part 4 Arteriovenous malformations: combined embolization and stereotactic radiosurgery for the treatment of large-volume, high-risk arteriovenous malformations, A.R. Plasencia et al; factors related to radiation injury after radiosurgery of arteriovenous malformations of the brain, A.A.F. De Salles et al; haemorrhage after radiosurgery for arteriovenous malformations - angiographic risk factors and prevention strategies with the aim of early obliteration, H.K. Inoue et al; 84 cases of cerebral arteriovenous malformations subjected to linac stereotactic radiosurgery - initial experience from Madras, India, K. Ganapathy et al. Part 5 Benign tumors: effects and prognostic factors in the treatment of craniopharyngioma by gamma knife, T. Kobayashi et al; statistical analysis of risk factors after gamma knife radiosurgery of acoustic neurinomas, R. Liscak et al; gamma knife treatment for pituitary adenomas, L. Junchao et al; single-fraction stereotactic irradiation for base of skull lesions, M.R. Pfeffer et al; gamma knife radiosurgery in the treatment of pineal region tumor, L. Junchao et al. Part 6 Malignant tumors: repeat