close menu
Bookswagon-24x7 online bookstore
close menu
My Account
Toll-Like Receptors: Methods and Protocols(517 Methods in Molecular Biology)

Toll-Like Receptors: Methods and Protocols(517 Methods in Molecular Biology)

          
5
4
3
2
1

Available


Premium quality
Premium quality
Bookswagon upholds the quality by delivering untarnished books. Quality, services and satisfaction are everything for us!
Easy Return
Easy return
Not satisfied with this product! Keep it in original condition and packaging to avail easy return policy.
Certified product
Certified product
First impression is the last impression! Address the book’s certification page, ISBN, publisher’s name, copyright page and print quality.
Secure Checkout
Secure checkout
Security at its finest! Login, browse, purchase and pay, every step is safe and secured.
Money back guarantee
Money-back guarantee:
It’s all about customers! For any kind of bad experience with the product, get your actual amount back after returning the product.
On time delivery
On-time delivery
At your doorstep on time! Get this book delivered without any delay.
Quantity:
Add to Wishlist

About the Book

In addition to their invaluable role in the fight against infection, Toll-Like Receptors (TLRs) in an under- or over-active state can lead to the pathogenesis of disease, making these receptors a key focal point for many research laboratories. In Toll-Like Receptors: Methods and Protocols, experts in the field contribute techniques currently used to study TLRs, their downstream signalling pathways, and their role in the pathogenesis of disease, with sections examining TLR expression and the application of genetic techniques and microarray analysis to TLR research. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and Notes sections highlighting tips on troubleshooting and avoiding known pitfalls.

Versatile and cutting-edge, Toll-Like Receptors: Methods and Protocols provides an ideal manual for a wide range of biologists and medical researchers studying these vital components of the immune system.



Table of Contents:
Methods to Detect and Analyze Toll-Like Receptors.- Expression Analysis of the Toll-Like Receptors in Human Peripheral Blood Mononuclear Cells.- Ligands, Cell-Based Models, and Readouts Required for Toll-Like Receptor Action.- Toll-Like Receptor Interactions Imaged by FRET Microscopy and GFP Fragment Reconstitution.- Predicting Toll-Like Receptor Structures and Characterizing Ligand Binding.- Bioinformatic Analysis of Toll-Like Receptor Sequences and Structures.- Expression, Purification, and Crystallization of Toll/Interleukin-1 Receptor (TIR) Domains.- Methods to Analyze Signal Transduction Downstream of Toll-Like Receptor Stimulation.- Proteomic Analysis of Protein Complexes in Toll-Like Receptor Biology.- 2D-DIGE: Comparative Proteomics of Cellular Signalling Pathways.- MAPPIT (Mammalian Protein–Protein Interaction Trap) Analysis of Early Steps in Toll-Like Receptor Signalling.- Analysis of the Functional Role of Toll-Like Receptor-4 Tyrosine Phosphorylation.- Analysis of Ubiquitin Degradation and Phosphorylation of Proteins.- The Generation of Highly Purified Primary Human Neutrophils and Assessment of Apoptosis in Response to Toll-Like Receptor Ligands.- Cellular Expression of A20 and ABIN-3 in Response to Toll-Like Receptor-4 Stimulation.- Characterisation of Viral Proteins that Inhibit Toll-Like Receptor Signal Transduction.- Genetic Techniques in Toll-Like Receptor Analysis.- Genetic Dissection of Toll-Like Receptor Signaling Using ENU Mutagenesis.- Microarray Experiments to Uncover Toll-Like Receptor Function.- Uncovering Novel Gene Function in Toll-Like Receptor Signalling Using siRNA.- Genotyping Methods to Analyse Polymorphisms in Toll-Like Receptors and Disease.- Toll-Like Receptors and Disease.- Experimental Models of Acute Infection and Toll-LikeReceptor Driven Septic Shock.- Toll-Like Receptors and Rheumatoid Arthritis.- Practical Techniques for Detection of Toll-Like Receptor-4 in the Human Intestine.- Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells.- Innate Immunity, Toll-Like Receptors, and Atherosclerosis: Mouse Models and Methods.- Generation of Parasite Antigens for Use in Toll-Like Receptor Research.- Biomarkers Measuring the Activity of Toll-Like Receptor Ligands in Clinical Development Programs.


Best Seller

| | See All

Product Details
  • ISBN-13: 9781934115725
  • Publisher: Humana Press Inc.
  • Publisher Imprint: Humana Press Inc.
  • Depth: 32
  • Height: 260 mm
  • No of Pages: 376
  • Series Title: 517 Methods in Molecular Biology
  • Sub Title: Methods and Protocols
  • Width: 193 mm
  • ISBN-10: 193411572X
  • Publisher Date: 01 Apr 2009
  • Binding: Hardback
  • Edition: 1
  • Language: English
  • Returnable: N
  • Spine Width: 25 mm
  • Weight: 1065 gr


Similar Products

How would you rate your experience shopping for books on Bookswagon?

Add Photo
Add Photo

Customer Reviews

REVIEWS           
Be The First to Review
Toll-Like Receptors: Methods and Protocols(517 Methods in Molecular Biology)
Humana Press Inc. -
Toll-Like Receptors: Methods and Protocols(517 Methods in Molecular Biology)
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Toll-Like Receptors: Methods and Protocols(517 Methods in Molecular Biology)

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book
    Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    New Arrivals

    | | See All


    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!
    ASK VIDYA