This completely revised and expanded Second Edition thoroughly examines tuberculosis from historical, theoretical, and clinical perspectives, including the most current discoveries. Containing 35 revised, rewritten, rearranged, and new chapters by nationally and internationally renowned experts, the updated Second Edition presents expanded coverage on the background of tuberculosis, including new chapters on tuberculosis control in low-income and low-prevalence countries, tuberculosis laboratories, and applied strategies of tuberculosis control complete coverage of new and emerging aspects of the disease, including expanded chapters on case finding and follow-up in high- and low-prevalence countries new chapters on the transmission of tuberculosis and international strain genotyping, tuberculosis infection control, coalition building for tuberculosis control, a model tuberculosis elimination program, tuberculosis and medical anthropology, international advocacy, health sector reform and tuberculosis, and DOTS-Plus tuberculosis care management updated information on outbreaks of multidrug-resistant tuberculosis, treatment of latent tuberculosis infection, and BCG vaccination over 50 new contributors and more! Providing updated information since the publication of the first edition six years ago and complete with over 2400 references, tables, and figures, the Second Edition is a must-read reference for pulmonary, respiratory, and infectious disease specialists; clinical microbiologists; pulmonologists; epidemiologists; immunologists; pathologists; physiologists; internists; public health physicians; local, regional, national, and international public health officials; directors of tuberculosis programs; allergists; scientific researchers; and graduate and medicinal students in these disciplines.

Table of Contents:
Programmatic Background A Historical Perspective on Tuberculosis and Its Control, Anne L. Davis Tuberculosis Control in Low-Income Countries, Donald A. Enarson Tuberculosis Control in Low-Prevalence Countries, Jaap F. Broekmans Tuberculosis Laboratories: The Centerpiece of National Tuberculosis Control Programs, Adalbert Laszlo Evaluation of Applied Strategies of Tuberculosis Control in the Developing World, Pierre Chaulet and Earl S. Hershfield Basic Aspects Epidemiology of Tuberculosis, George W. Comstock Bacteriology of Tuberculosis, Jacques Grosset, Chantal Truffot-Pernot, and Emmanuelle Cambau Immunology of Tuberculosis, Thomas M. Daniel, W. Henry Boom, and Jerrold J. Ellner Transmission of Tuberculosis, Edward A. Nardell and Willy F. Piessens Pathogenesis of Tuberculosis, Willy F. Piessens and Edward A. Nardell Mycobacterial Strain Genotyping, Nancy D. Connell and Barry N. Kreiswirth Clinical Aspects Tuberculin Skin Testing, Richard I. Menzies Case Finding in High- and Low-Prevalence Countries, Hans L. Rieder Diagnosis of Tuberculosis, Philip A. LoBue, Sharon Perry, and Antonino Catanzaro Contact Follow-Up in High- and Low-Prevalence Countries, Sue C. Etkind and Jaap Veen Treatment of Tuberculosis, Paula I. Fujiwara, Patricia M. Simone, and Sonal S. Munsiff Responding to Outbreaks of Multidrug-Resistant Tuberculosis: Introducing DOTS-Plus, Paul E. Farmer, Jim Yong Kim, Carole D. Mitnick, and Ralph Temperi Treatment of Latent Tuberculosis Infection, David L. Cohn and Wafaa M. El-Sadr BCG Vaccines and Vaccination, Paul E. M. Fine Special Problems Tuberculosis and Human Immunodeficiency Virus Infection, Philip C. Hopewell and Richard E. Chaisson Tuberculosis in Children, Flor M. Muñoz and Jeffrey R. Starke Case Management: The Key to a Successful Tuberculosis-Control Program, Bonita T. Mangura and Karen E. Ga