Ulcerative Colitis: The Complete Guide to Medical Management serves as the definitive source for medical management of ulcerative colitis (UC). Dr. Gary R. Lichtenstein, along with Dr. Ellen J. Scherl, have collaborated with over 60 experts from around the world to provide gastroenterologists and those in training with the necessary information to successfully manage the patient with ulcerative colitis. Sections Include: • General o The role of the FDA in drug development; pediatric considerations; disease modifiers; and more • Medications o Antibiotic use in treatment of UC; oral novel biological therapies for UC; calcineurin inhibitors use in UC; novel biologic and non-biologic therapy for UC; and more • Specific Clinical Presentations o Medical management of toxic megacolon; management of extraintestinal manifestations; medical therapy of left-sided UC; use of prebiotics and probiotics; maintenance of remission; and more Features: • Color images, graphs, and tables • Extensive index that includes cross-referencing to Crohn’s Disease: The Complete Guide to Medical Management • Comprehensive references at the end of each chapter Organized into an easy-to-reference format, Ulcerative Colitis: The Complete Guide to Medical Management threads theory into practice and provides gastroenterology professionals with the most comprehensive information available. The other side of inflammatory bowel disease is covered in Drs. Gary R. Lichtenstein and Ellen J. Scherl’s Crohn’s Disease: The Complete Guide to Medical Management. All gastroenterologists will find both books to be essential for future practice in the treatment and care of their patients with either Crohn’s disease or ulcerative colitis, as well as in the overall management of those with inflammatory bowel disease.

Table of Contents:
Dedication Acknowledgments About the Editor and Associate Editor Contributing Authors Introduction Prologue Historical Perspective of Ulcerative Colitis Ming V. Lin, MD; Wojciech Blonski, MD, PhD; David Kotlyar, MD; and Gary R. Lichtenstein, MD, FACP, FACG, AGAF Section I General Chapter 1 The Natural History of Inflammatory Bowel Disease Pietro G. Andres, MD and Lawrence S. Friedman, MD Chapter 2 Clinical Research in Inflammatory Bowel Disease: Placebo Response in Clinical Trials Chinyu Su, MD and James D. Lewis, MD, MSCE Chapter 3 The Role of the FDA in Drug Development in Inflammatory Bowel Disease Alan C. Moss, MD, FACG and Adam S. Cheifetz, MD Chapter 4 Utility of Animal Models for the Study and Treatment of Inflammatory Bowel Disease Ashish Chawla, MD and Kenneth Simpson, BVM&S, PhD Chapter 5 Pediatric Considerations in Medical Therapy in Patients With Inflammatory Bowel Disease Louis R. Ghanem, MD, PhD and Robert N. Baldassano, MD Chapter 6 The Limitations of Applying Evidence-Based Medicine to Inflammatory Bowel Disease: What We Do Not Learn From Clinical Trials Joshua R. Korzenik, MD and Corey A. Siegel, MD Chapter 7 Disease Modifiers in Inflammatory Bowel Disease Jaime A. Oviedo, MD and Francis A. Farraye, MD, MSc, FACP, FACG Chapter 8 Fertility and Pregnancy in Inflammatory Bowel Disease Jeffry A. Katz, MD and Vinita Elizabeth Jacob, MD Chapter 9 Diversion Colitis Eugeni Dom\u00e8nech, MD, PhD and Miguel A. Gassull, MD, PhD Chapter 10 Medication Adherence in Inflammatory Bowel Disease Sunanda V. Kane, MD, MSPH, FACG, FACP, AGAF Section II Medications Chapter 11 General Principles of Medical Therapy of Ulcerative Colitis Sonia Friedman, MD, FACP Chapter 12 Assessment of Disease Activity in Ulcerative Colitis Anthony L. Rosa, MD and Thomas A. Judge, MD Chapter 13 Current and Future Oral Mesalamine Derivative Use in Ulcerative Colitis Lloyd Sutherland, MDCM, MSc, FRCP(C), FACP Chapter 14 Current and Future Topical Mesalamine Derivatives in Ulcerative Colitis Jeffrey W. Nathanson, MD and Russell D. Cohen, MD Chapter 15 Antibiotics in Ulcerative Colitis Kim L. Isaacs, MD, PhD Chapter 16 Oral and Parenteral Corticosteroids in Ulcerative Colitis Leonard Baidoo, MD and Gary R. Lichtenstein, MD, FACP, FACG, AGAF Chapter 17 Topical Corticosteroid Use in Ulcerative Colitis Seymour Katz, MD, FACP, MACG Chapter 18 6-Mercaptopurine and Azathioprine Use in Ulcerative Colitis Marla C. Dubinsky, MD Chapter 19 Azathioprine Metabolism in Inflammatory Bowel Disease: A PhysicianÆs Guide to Metabolite Testing Carmen Cuffari, MD Chapter 20 Methotrexate in the Treatment of Ulcerative Colitis Ellen J. Scherl, MD, FACP, AGAF; Vinita Elizabeth Jacob, MD; Brian P. Bosworth, MD; Ryan Urquhart Warren, MD; and Harrison Lakehomer, BA Chapter 21 Calcineurin Inhibitors (Cyclosporine, Tacrolimus, Sirolimus) and Mycophenolate Motefil Use in Ulcerative Colitis Hans Herfarth, MD, PhD and J\u00fcrgen Sch\u00f6lmerich, MD, PhD Chapter 22 Infliximab Use in Ulcerative Colitis Wojciech Blonski, MD, PhD; Antoni Stadnicki, MD, PhD; Gary R. Lichtenstein, MD, FACP, FACG, AGAF;