Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume 2 presents a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the structure, distribution, and variations of rod-shaped microtubulated bodies; morphology of intracytoplasmic filaments; melanosome-producing and melanosome-containing cells in tumours; myofilaments in striated muscle; and pathological variations in size, shape, and numbers of microbodies. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, pathologists, students, and researchers.

Table of Contents:
7 Lysosomes Introduction (History, Classification and Nomenclature) Heterolysosomes and Autolysosomes Lamellar Cup-Shaped Lysosomes Multivesicular Bodies and R-Bodies Lipofuscin (Residual Bodies) Myelinoid Membranes, Myelin Figures and Myelinosomes Erythrophagosomes and Erythrophagolysosomes Siderosomes, Haemosiderin and Ferritin Lysosomes and Residual Bodies in Tumours Lysosomes in Erythrocytes Lysosomes in Neutrophil Leucocytes Lysosomes in Eosinophil Leucocytes Lysosomes in Monocytes and Macrophages Lysosomes in Melanosis Coli and Some Other Melanoses Lysosomes in Melanosis Duodeni Lysosomes in Malakoplakia Lysosomes in Granular Cell Tumors Lysosomes in Rheumatoid Arthritis Lysosomes in the Liver of the Tumor-Bearing Host Angulate Lysosomes Lysosomes in Mucopolysaccharidoses Lysosomes in Metachromatic Leucodystrophy (Sulphatoidosis) Curvilinear Bodies in Lysosomes Collagen in Lysosomes Glycogen in Lysosomes (Glycogenosomes) Metals in Lysosomes Aurosomes Platinosomes Interlysosomal Crystalline Plates (Zipper-like Structures) References 8 Microbodies (Peroxisomes, Microperoxisomes and Catalosomes) Introduction Structure and Normal Variations Pathological Variations in Size, Shape and Numbers References 9 Melanosomes Introduction Morphology and Normal Variations Alterations in Melanosomes in Melanomas and Pigmentary Disorders Granular Melanosomes Balloon Melanosomes Giant Melanosomes Melanosome-Producing and Melanosome-Containing Cells in Tumors References 10 Rod-Shaped Microtubulated Bodies Introduction Structure, Distribution and Variations Rod-Shaped Microtubulated Body in Vasoformative Tumors References 11 Intracytoplasmic Filaments Introduction Myofilaments in Striated Muscle Ring Fibers Myofibrillary Degeneration Morphological Alterations of the Z-Line Myofilaments in Rhabdomyoma and Rhabdomyosarcoma Myofilaments in Smooth Muscle Myofilaments in Leiomyoma and Leiomyosarcoma Myofilaments in Cells Other than Muscle Myofibroblasts and Myofibroblastoma Intermediate Filaments in Normal and Pathological States (Including Neoplastic) Mallory's Bodies Globular Filamentous Bodies Crystals and Crystalloids of Intracytoplasmic Filaments Crystalline Filamentous Cylinders Asteroid Bodies References 12 Microtubules Introduction Structure, Function and Variations References 13 Cytoplasmic Matrix and Its Inclusions Introduction The Dark Cell-Light Cell Phenomenon Dark and Light Cells in Tumors Glycogen Polyglucosan Bodies (Corpora Amylacea, Lafora's Bodies, Lafora-like Bodies, Bielschowsky's Bodies and Amylopectin Bodies) Lipid Crystalline Inclusions Fibrin Heinz Bodies Porphyrin Inclusions Intracellular and Intracytoplasmic Collagen Intracytoplasmic Banded Structures Intracytoplasmic Desmosomes Intracytoplasmic Canaliculi and Lumina Intracytoplasmic Nucleolus-like Bodies (Nematosome, Nuage, Dense Body, Honey-Comb Body, Ribosomal Body) Viral Inclusions References 14 Cell Membrane and Coat Introduction Cell Membrane T-Tubule Networks Basement Membrane and Basal Lamina Alterations in the Basal Lamina Basal Lamina in Alport's Syndrome Basal Lamina in Dense Deposit Disease Coat of Free Surfaces External Lamina Glycocalyceal Bodies and Filamentous Core Rootlets Spherical Microparticles Crystals in Basal Lamina (Striated Lamellar Structures, Fibrin and Others) References 15 Cell Junctions Introduction Structure and Function of Cell Junctions Alterations of Cell Junctions in Neoplasia Diagnostic Value of Cell Junctions in Tumors Cell Junctions in Connective Tissues and Haemopoietic Tissues References 16 Endocytotic Structures and Cell Processes Introduction Endocytotic Vesicles and Vacuoles Micropinocytosis Vermiformis Langerhans' Cell Granules (Birkbeck's Granules) Emperipolesis Cytoplasmic Bubbling, Blebs and Blisters Microvilli and Stereocilia Morphological Alterations in Microvilli Vermipodia Cell Processes in Hairy Cell Leukaemia Ropalocytes and Ropalopodia Uropod of the Lymphocyte Foot Processes of Podocytes Cilia, Flagella and Sperm Tails Single, Primary or Oligocilia Atypical Cilia Atypical Basal Bodies (Half Centrioles, Giant Centrioles and Others) Immotile Cilia Syndrome References 17 Extracellular Matrix (Extracellular Components) Introduction (Classification and Nomenclature of Fibrous Components) Collagen, Filaments, Fibrils and Fibers Collagen in Fossils and Mummies Anchoring Fibrils Spiny Collagen Fibrous Long-Spacing Collagen Segment Long-Spacing Collagen Giant Collagen Fibrils and Amianthoid Fibers Spiralled Collagen (Poorly Packed Collagen and Frayed Collagen) Elastic Fibers, Elaunin Fibers and Oxytalan Fibers Calcified Elastic Fibers Amyloid Fibrin Proteoglycan Particles (Matrix Granules) Calcification (Matrical Lipidic Debris, Matrix Vesicles, Calcifying Collagen and Calcifying Secretions) References Nomogram Index