This volume provides a synthesis of the compeiling research that has emerged describing the intricate interrelationships between the pathophysiology of vascular Dementia (VaD) and neuropathological features of other degenerative diseases. Binding together clinical relevant aspects of the disease, this book integrates findings from studies that have focused on the neuropathology, neuropsychology and behavioral neurology of VaD. Unique in its presentation that reviews VaD in depth from basic etiology to clinical practice, this volume will be extremely attractive to both clinicians and researchers in general and behavioral neurology, neuropsychiatry, geriatric psychiatry and clinical neuropsychology.

Table of Contents:
Part I. Introduction; The Aging Population and the Importance of Vascular Dementia Kelly L. Lange and Robert H. Paul; Clinical Forms of Vascular Dementia Gustavo C. Roman; Neuropathological Substrates of Vascular Ischemic Dementia Kurt A. Jellinger; Diagnosis of Vascular Dementia: Conceptual Challenges Jose G. Merino and Vladimir Hachinski; Part II. Basic Mechanisms of Vascular Dementia; Cerebral Hemodynamics in the Elderly Jorge M. Serrador and Lewis A. Lipsitz; The CADASIL Syndrome and Other Genetic Causes of Stroke and Vascular Dementia Stephen Salloway and Sophie Desbiens; Estrogen, the Cerebrovascular System, and Dementia Sharon X. C. Yang and George A. Kuchel; Hypertension and Cerebrovascular Disease: Effects of Hypertension on Young and Middle-Aged Rhesus Monkeys Mark B. Moss and Elizabeth M. Jonak; Part III. The Impact of Vascular Dementia on Cognitive, Psychiatric, and Daily Living; The Cognitive Profile of Vascular Dementia Angela Lee Jefferson, Adam M. Brickman, Mark Aloia, and Robert H. Paul; Progression of Cognitive Impairments Associated with Cerebrovascular Disease Sally Stephens, Raj Kalaria, Rose Anne Kenny, and Clive Ballard; Neuropsychiatric Correlates of Vascular Injury: Vascular Dementia and Related Neurobehavioral Syndromes Anand Kumar, Helen Lavretsky, and Ebrahim Haroon; Functional Impairment in Vascular Dementia Patricia A. Boyle and Deborah Cahn-Weiner; Part IV. Neuroimaging of Vascular Dementia; Functional Brain Imaging of Cerebrovascular Disease Ronald Cohen, Lawrence Sweet, David F. Tate, and Marc Fisher; Contributions of Subcortical Lacunar Infarcts to Cognitive Impairment in Older Persons Dan Mungas; White Matter Hyperintensities and Cognition David J. Moser, Jason E. Kanz, and Kelly Davis Garrett; Poststroke Dementia: The Role of Strategic Infarcts Anelyssa D' Abreu and Brian R. Ott; Part V. Interactions Between Vascular Dementia and Alzheimer's Disease; Understanding Incidence and Prevalence Rates in Mixed Dementia John Gunstad and Jeffery Browndyke; Vascular Basement Membrane Abnormalities and Alzheimer's Disease Edward G. Stopa, Brian D. Zipser, and John E. Donahue; Amyloid Beta and the Cerebral Vasculature Paula Grammas; Cerebrovascular Disease and the Expression of Alzheimer's Disease Margaret M. Esiri and Zsuzsanna Nagy; The Neuropsychological Differentiation Between Alzheimer's Disease and Subcortical Vascular Dementia David J. Libon, Stephen Scheinthal, Dana L. Penney, and Rod Swenson; Part VI. Clinical Management of Vascular Dementia; Pharmacological Treatment of Vascular Dementia Timo Erkinjuntti, Gustavo Roman, Serge Gauthier, and Kenneth Rockwood; Understanding and Managing Caregiver Burden in Cerebrovascular Disease Geoffrey Tremont, Jennifer Duncan Davis, and Mary Beth Spitznagel; Quality of Life in Patients with Vascular Dementia Rebecca E. Ready and Brian R. Ott; Approaches to Neuroprotection and Recovery Enhancement after Acute Stroke Marc Fisher and Magdy Selim