Vsevolod V Gurevich

Vsevolod V GurevichDr. Gurevich obtained his PhD at the Shemyakin Institute of Bioorganic Chemistry, in Moscow, Russia. He performed his postdoctoral studies at Thomas Jefferson University in Philadelphia and is currently Professor of Pharmacology at Vanderbilt Universty. He is a Cornelius Vanderbilt Endowed Chair. He has published more than 220 papers in reputed journals and has been serving as an editorial board member of several journals. The main focus of the work in his lab is structure-function studies of arrestins, that bind almost all of >800 G protein-coupled receptors in humans and dozens of non-receptor signaling proteins. The lab is using biochemistry, biophysics, and cell biology to elucidate arrestin elements involved in the interactions with various binding partners and to construct signaling-biased arrestins specifically targeting individual receptors and signaling pathways. Read More Read Less

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G Protein-Coupled Receptor Kinases37 %
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Structural Basis of Arrestin Functions37 %
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Arrestins - Pharmacology and Therapeutic Potential37 %
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G Protein-Coupled Receptor Kinases37 %
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Structural Basis of Arrestin Functions37 %
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Arrestins - Pharmacology and Therapeutic Potential37 %
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Arrestins17 % NR
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01 May 2022
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The Structural Basis of Arrestin Functions2 % NR
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